Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9036801 | 0.81 | MAPK1 (0.54) | TSHRHPGDLMNAALDH1A1HTT | |
| SCHEMBL4310722 | 0.78 | TSHR (0.84) | TSHRHPGDAKR1C1LMNANPC1 | |
| SCHEMBL7212601 | 0.78 | ALDH1A1 (0.51) | TSHRLMNAFAAHMGLLABHD6 | |
| SCHEMBL8349346 | 0.77 | TSHR (0.68) | TSHRHPGDAKR1C1LMNANPC1 | |
| SCHEMBL7217691 | 0.76 | ALDH1A1 (0.60) | TSHRLMNAALDH1A1HTTHSD17B10 | |
| SCHEMBL31350761 | 0.76 | FAAH (0.52) | TSHRHPGDLMNAFAAHMGLL | |
| SCHEMBL7218802 | 0.75 | HPGD (0.73) | TSHRHPGDAKR1C1LMNANPC1 | |
| SCHEMBL7212381 | 0.74 | HTT (0.55) | TSHRHPGDLMNAFAAHMGLL | |
| Ethylene SCHEMBL8518097 | 0.74 | TSHR (0.64) | TSHRHPGDAKR1C1LMNANPC1 | |
| SCHEMBL10197843 | 0.73 | HPGD (0.71) | TSHRHPGDAKR1C1LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE38257-E1 | Piperdine derivatives and hypotensives containing the same | AJINOMOTO CO., INC. (JP) | 2003-09-23 | — | — | US | disclosed |