Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.50 |
| ▸ | SETD7 | Q8WTS6 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7212381 | 0.82 | HTT (0.55) | ALDH1A1LMNAFAAHMGLLABHD6 | |
| SCHEMBL4453090 | 0.78 | ALDH1A1 (0.77) | ALDH1A1LMNAHTTMEN1KMT2A | |
| SCHEMBL7213758 | 0.78 | TSHR (0.54) | ALDH1A1LMNAFAAHMGLLABHD6 | |
| SCHEMBL17595252 | 0.77 | ALDH1A1 (0.62) | ALDH1A1LMNAHTTMEN1KMT2A | |
| SCHEMBL3582934 | 0.75 | ALDH1A1 (0.68) | ALDH1A1LMNAHTTTP53TSHR | |
| SCHEMBL6430908 | 0.75 | ALDH1A1 (0.68) | ALDH1A1LMNAHTTTSHRMEN1 | |
| SCHEMBL25247976 | 0.73 | ALDH1A1 (0.66) | ALDH1A1LMNAHTTMEN1KMT2A | |
| SCHEMBL14720666 | 0.73 | ALDH1A1 (0.66) | ALDH1A1LMNAHTTMEN1KMT2A | |
| SCHEMBL28570849 | 0.73 | ALDH1A1 (0.66) | ALDH1A1LMNAHTTMEN1KMT2A | |
| SCHEMBL8407368 | 0.73 | ALDH1A1 (0.66) | ALDH1A1LMNAHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE38257-E1 | Piperdine derivatives and hypotensives containing the same | AJINOMOTO CO., INC. (JP) | 2003-09-23 | — | — | US | disclosed |
| US-5393890-A | Piperidine derivatives and hypotensives containing the same | AJINOMOTO CO., INC. (JP) | 1995-02-28 | — | — | US | disclosed |