Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 3/20 | 0.33 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.33 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10072218 | 0.89 | TSHR (0.46) | TSHRALDH1A1MAPK1TDP1FGFR4 | |
| Sulfuric Acid SCHEMBL7212412 | 0.74 | TSHR (0.42) | TSHRALDH1A1MAPK1TDP1FGFR4 | |
| Sulfuric Acid SCHEMBL27873789 | 0.72 | TSHR (0.42) | TSHRALDH1A1MAPK1TDP1FGFR4 | |
| SCHEMBL31489136 | 0.71 | TSHR (0.36) | TSHRALDH1A1MAPK1TDP1FGFR4 | |
| SCHEMBL4543606 | 0.71 | TGM2 (0.39) | TSHRALDH1A1MAPK1TDP1FGFR4 | |
| SCHEMBL10715597 | 0.71 | TSHR (0.36) | TSHRALDH1A1MAPK1TDP1FGFR4 | |
| Sulfuric Acid SCHEMBL28767332 | 0.70 | TSHR (0.80) | TSHRALDH1A1MAPK1TDP1TGM2 | |
| Acrylamide SCHEMBL27659043 | 0.69 | ALDH1A1 (0.73) | TSHRALDH1A1TDP1FGFR4LMNA | |
| Acrylamide SCHEMBL692432 | 0.69 | ALDH1A1 (0.73) | TSHRALDH1A1TDP1FGFR4LMNA | |
| SCHEMBL151658 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2723308-B2 | COSMETIC COMPOSITION COMPRISING AT LEAST ONE PARTICULAR AMPHOTERIC POLYMER AND AT LEAST ONE PARTICULAR CONDITIONING AGENT | OREAL (FR) | 2023-08-30 | — | — | EP | claimed |
| EP-2723308-B1 | COSMETIC COMPOSITION COMPRISING AT LEAST ONE PARTICULAR AMPHOTERIC POLYMER AND AT LEAST ONE PARTICULAR CONDITIONING AGENT | L'ORÉAL (FR) | 2017-08-02 | — | — | EP | claimed |
| US-6617292-B2 | Said shampoo gives hair good styling retention and a certain volume of | L'OREAL (FR) | 2003-09-09 | — | — | US | claimed |