Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Acrylamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.73 |
| ▸ | TSHR | P16473 | 3/20 | 0.73 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.73 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylamide SCHEMBL27659043 | 1.00 | ALDH1A1 (0.73) | ALDH1A1TSHRFGFR4BLMKDM4E | |
| Acrylamide SCHEMBL28217381 | 0.97 | ALDH1A1 (0.69) | ALDH1A1TSHRFGFR4BLMKDM4E | |
| Acrylamide SCHEMBL28327605 | 0.97 | ALDH1A1 (0.69) | ALDH1A1TSHRFGFR4BLMKDM4E | |
| Acrylamide SCHEMBL28248949 | 0.97 | ALDH1A1 (0.69) | ALDH1A1TSHRFGFR4BLMKDM4E | |
| Acrylamide SCHEMBL28788499 | 0.97 | ALDH1A1 (0.69) | ALDH1A1TSHRFGFR4BLMKDM4E | |
| Acrylamide SCHEMBL7987485 | 0.97 | ALDH1A1 (0.69) | ALDH1A1TSHRFGFR4BLMKDM4E | |
| Acrylamide SCHEMBL28835519 | 0.97 | ALDH1A1 (0.69) | ALDH1A1TSHRFGFR4BLMKDM4E | |
| Acrylamide SCHEMBL28253722 | 0.97 | ALDH1A1 (0.69) | ALDH1A1TSHRFGFR4BLMKDM4E | |
| Acrylamide SCHEMBL28881120 | 0.97 | ALDH1A1 (0.69) | ALDH1A1TSHRFGFR4BLMKDM4E | |
| Acrylamide SCHEMBL14118867 | 0.97 | ALDH1A1 (0.69) | ALDH1A1TSHRFGFR4BLMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 333 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113651903-B | Method for preparing large-particle-size polybutadiene latex based on high molecular agglomeration technology | 上海中化科技有限公司 | 2023-05-26 | — | — | CN | claimed |
| CN-113651903-A | Method for preparing large-particle-size polybutadiene latex based on polymer agglomeration technology | 上海中化科技有限公司 | 2021-11-16 | — | — | CN | claimed |
| CN-112807487-A | Nano polysaccharide complex and its preparation method and use | 宝龄富锦生技股份有限公司 | 2021-05-18 | — | — | CN | claimed |
| CN-110683823-A | Salt lake salt pan anti-seepage agent and preparation and construction method thereof | 中蓝长化工程科技有限公司 | 2020-01-14 | — | — | CN | claimed |
| CN-109937043-A | The drug salts and its crystal form of N- (2- (2- (dimethylamino) ethyoxyl) -4- methoxyl group -5- ((4- (1- Methyl-1H-indole -3- base) pyrimidine -2-base) amino) phenyl) acrylamide | 贝达医药公司 | 2019-06-25 | — | — | CN | claimed |
| CN-106348569-A | Low-dosage slurry curing agent composition, and preparation method and application method thereof | 四川铁科新型建材有限公司 | 2017-01-25 | — | — | CN | claimed |
| US-20100196289-A1 | DOUBLE LAYERED OXIDE AND HYDROXIDE PIGMENTS AND METHOD OF THEIR PREPARATION | RELIVIA S.R.L. (IT) | 2010-08-05 | — | — | US | claimed |
| EP-1899421-A1 | DOUBLE LAYERED METAL OXIDE AND HYDROXIDE PIGMENTS AND METHOD OF THEIR PREPARATION | Ghisalberti, Carlo (BR) | 2008-03-19 | — | — | EP | claimed |
| WO-2007083184-A2 | COSMETIC DERMATOLOGY IN ACNEIC AND COMEDOGENIC SKIN | GHISALBERTI CARLO (BR) | 2007-07-26 | — | — | WO | claimed |
| WO-2007083174-A1 | CURATIVE PIGMENTS AND MAKE-UP COMPRISING THEREOF | GHISALBERTI CARLO (BR) | 2007-07-26 | — | — | WO | claimed |
| WO-2006136880-A1 | DOUBLE LAYERED METAL OXIDE AND HYDROXIDE PIGMENTS AND METHOD OF THEIR PREPARATION | GHISALBERTI CARLO (BR) | 2006-12-28 | — | — | WO | claimed |
| US-20050205837-A1 | Polishing composition and polishing method | FUJIMI INCORPORATED (JP) | 2005-09-22 | — | — | US | claimed |
| US-12614730-B2 | Aqueous binder composition for an electrode and methods for producing the same | HERCULES LLC (US) | 2026-04-28 | — | — | US | disclosed |
| CN-116640060-B | Method for preparing low-carbon ester by one-step method of methanol and methyl acetate | 华东理工大学 | 2025-05-23 | — | — | CN | disclosed |
| CN-119746883-A | Acrolein oxidation catalyst and preparation process thereof | 江西申麦新材料科技有限公司 | 2025-04-04 | — | — | CN | disclosed |
| CN-119746879-A | Propylene oxidation catalyst and preparation process thereof | 江西申麦新材料科技有限公司 | 2025-04-04 | — | — | CN | disclosed |
| US-3966810-A | Process for hydrating a nitrile to the corresponding amide | KURATA TOKUZO | 1976-06-29 | — | — | US | disclosed |
| US-3947518-A | Process for purifying acrylamides | NITTO KAGAKU KOGYO KABUSHIKI KAISHA (JA) | 1976-03-30 | — | — | US | disclosed |
| US-3946061-A | DISPERSANTS, FLOCCULANTS, SEQUESTERING | BUCKMAN LABORATORIES, INC. (US) | 1976-03-23 | — | — | US | disclosed |
| US-3939205-A | TO FORM AN AMIDE, COPPER CATALYST | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) | 1976-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100196289-A1 | DOUBLE LAYERED OXIDE AND HYDROXIDE PIGMENTS AND METHOD OF THEIR PREPARATION | SOD1, SOD3, GPX4 | ALDH1A1 3393/4885TSHR 3480/4885FGFR4 4037/4885 |
| US-12614730-B2 | Aqueous binder composition for an electrode and methods for producing the same | MLEC, SDC1, CLTA | ALDH1A1 3544/4885TSHR 3067/4885FGFR4 4527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.