SCHEMBL7212494

SCHEMBL7212494

CC1=Cc2c(-c3cccc4ccccc34)cccc2C1[Hf](Cl)(Cl)(C1C(C)=Cc2c(-c3cccc4ccccc34)cccc21)[GeH](C)C

nearest known ligand 0.32

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 2/20 0.32
HTR7 P34969 2/20 0.32
KDM4E B2RXH2 1/20 0.32
CA12 O43570 2/20 0.31
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31
CA9 Q16790 2/20 0.31
CYP2D6 P10635 1/20 0.30
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30
SLC6A3 Q01959 1/20 0.30
ALDH1A1 P00352 1/20 0.30
CYP2A6 P11509 1/20 0.30
DHFR P00374 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5853881 0.82 KDM4E (0.32) KDM4ECA12CA1CA2CA9
SCHEMBL6914199 0.82 ALDH1A1 (0.32) KDM4ECA12CA1CA2CA9
SCHEMBL818878 0.82 KDM4E (0.34) KDM4ECA12CA1CA2CA9
SCHEMBL7933102 0.82 KDM4E (0.32) KDM4ECA12CA1CA2CA9
SCHEMBL8204449 0.80 KDM4E (0.33) HTR1AHTR7KDM4ECA12CA1
Hydrochloric Acid SCHEMBL6434572 0.80 ALDH1A1 (0.34) HTR1AHTR7KDM4ECA12CA1
SCHEMBL8604969 0.80 KDM4E (0.33) KDM4ECA12CA1CA2CA9
SCHEMBL8602732 0.80 KDM4E (0.30) KDM4ECA12CA1CA2CA9
SCHEMBL7933047 0.79
SCHEMBL7926735 0.79 ALDH1A1 (0.32) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6515037-B2 A molded foam using a copolymer of propylene and an alpha-omega diene having been polymerized in the presence of a metallocene supported catalyst and foaming agent; uniform and fine foamed cells; high foaming magnification; extrusion CHISSO CORPORATION (JP) 2003-02-04 US disclosed
US-6337372-B1 ADDITIOIN POLYMERIZATION OF OLEFINS AND PROPYLENE FOR BLOCK POLYMERS CHISSO CORPORATION (JP) 2002-01-08 US disclosed
US-20010031834-A1 Using coordination catalyst; flexibility, elasticity; molding materials CHISSO CORPORATION 2001-10-18 US disclosed
US-20010020045-A1 Polypropylene base resin composition for foam-molding, foamed article using the same composition, production process for the same foamed article and foam-molded product using the foamed-article CHISSO CORPORATION 2001-09-06 US disclosed