Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7939078 | 0.88 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL7926735 | 0.86 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL7933119 | 0.84 | ALOX5 (0.33) | — | |
| SCHEMBL7926522 | 0.84 | — | — | |
| SCHEMBL7926987 | 0.83 | BRD4 (0.31) | — | |
| SCHEMBL818878 | 0.82 | KDM4E (0.34) | KDM4ECA12CA1CA2CA9 | |
| SCHEMBL5853881 | 0.82 | KDM4E (0.32) | KDM4ECA12CA1CA2CA9 | |
| SCHEMBL6914199 | 0.82 | ALDH1A1 (0.32) | KDM4EKDM1ACA12CA1CA2 | |
| SCHEMBL7212494 | 0.82 | HTR1A (0.32) | KDM4ECA12CA1CA2CA9 | |
| SCHEMBL8204449 | 0.80 | KDM4E (0.33) | KDM4EKDM1ACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6184402-B1 | RESOLUTION OF A STEREOISOMERIC MIXTURE OF SPECIFIC METALLOCENE COMPLEXES BRIDGED WITH A TRANSITION METAL HAVING AN OXYGEN BOND ATTACHED, I.E., A MU-OXO COMPLEX; HYDROLYSIS IN THE PRESENCE OF A BASE; SEPARATION OF MESO FORM FROM MIXES | CHISSO CORPORATION (JP) | 2001-02-06 | — | — | US | disclosed |