Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 3/20 | 0.32 |
| ▸ | ACHE | P22303 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7205105 | 0.89 | RECQL (0.37) | LMNAALDH1A1HRH3BCHEACHE | |
| SCHEMBL3825844 | 0.85 | LMNA (0.41) | LMNAALDH1A1L3MBTL1MAPTHPGD | |
| SCHEMBL7204740 | 0.83 | TSHR (0.38) | LMNAALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL7212661 | 0.83 | CSNK2A2 (0.37) | LMNAMEN1KMT2AHTT | |
| SCHEMBL7206799 | 0.81 | LMNA (0.33) | LMNAALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL7205833 | 0.75 | ALDH1A1 (0.42) | LMNAALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL7212676 | 0.75 | RAF1 (0.33) | KMT2A | |
| SCHEMBL7211153 | 0.75 | KDM4E (0.30) | ALDH1A1MAPTHSD17B10 | |
| SCHEMBL7208761 | 0.73 | BCHE (0.39) | ALDH1A1BCHEACHEHTTRAB9A | |
| SCHEMBL7206793 | 0.73 | BCHE (0.39) | ALDH1A1BCHEACHEHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060183-B1 | 5'-DEOXYCYTIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2003-04-23 | — | — | EP | disclosed |
| EP-1060183-A1 | 5'-DEOXYCYTIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-12-20 | — | — | EP | disclosed |
| WO-1999040099-A1 | 5'-DEOXYCYTIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1999-08-12 | — | — | WO | disclosed |