Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3825844 | 0.89 | LMNA (0.41) | LMNAMAPK1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7212657 | 0.84 | NAAA (0.43) | LMNARAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL7205105 | 0.84 | RECQL (0.37) | HSD17B10LMNAKDM4EALDH1A1MAPT | |
| SCHEMBL7212661 | 0.84 | CSNK2A2 (0.37) | TSHRLMNAMAPK1KDM4EMEN1 | |
| SCHEMBL7207482 | 0.83 | LMNA (0.35) | HSD17B10LMNARAB9ASMN1; SMN2HPGD | |
| SCHEMBL7211139 | 0.82 | SMN1; SMN2 (0.34) | TSHRLMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL7206799 | 0.82 | LMNA (0.33) | TSHRLMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL7204392 | 0.79 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL7205752 | 0.78 | BCHE (0.41) | TSHRRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL7208761 | 0.76 | BCHE (0.39) | TSHRRAB9ASMN1; SMN2NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060183-B1 | 5'-DEOXYCYTIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2003-04-23 | — | — | EP | disclosed |
| EP-1060183-A1 | 5'-DEOXYCYTIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-12-20 | — | — | EP | disclosed |
| WO-1999040099-A1 | 5'-DEOXYCYTIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1999-08-12 | — | — | WO | disclosed |