Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 10/20 | 0.54 |
| ▸ | CXCR1 | P25024 | 9/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7211897 | 0.88 | CXCR2 (0.50) | CXCR2DRD2 | |
| SCHEMBL7211780 | 0.85 | CXCR2 (0.50) | CXCR2CXCR1CA1CA2 | |
| SCHEMBL7211935 | 0.84 | CXCR2 (0.64) | CXCR2CXCR1TDP1L3MBTL1 | |
| SCHEMBL4586237 | 0.81 | CXCR2 (0.56) | CXCR2CXCR1 | |
| SCHEMBL4587033 | 0.79 | CXCR2 (0.58) | CXCR2CXCR1 | |
| SCHEMBL7211797 | 0.77 | MAOA (0.48) | DRD2TDP1CA12CA1CA2 | |
| SCHEMBL7503016 | 0.76 | CXCR2 (0.56) | CXCR2CXCR1 | |
| SCHEMBL31203458 | 0.76 | CA1 (0.53) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL7216748 | 0.73 | ALDH1A1 (0.45) | DRD2TDP1CA12CA1CA2 | |
| SCHEMBL4051645 | 0.73 | CA1 (0.58) | TDP1L3MBTL1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1237548-A4 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2003-07-23 | — | — | EP | claimed |
| EP-1237548-A1 | IL-8 RECEPTOR ANTAGONISTS | SmithKline Beecham Corporation (US) | 2002-09-11 | — | — | EP | claimed |
| WO-2001034141-A1 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-17 | — | — | WO | claimed |
| EP-1237548-A4 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2003-07-23 | — | — | EP | disclosed |
| EP-1237548-A1 | IL-8 RECEPTOR ANTAGONISTS | SmithKline Beecham Corporation (US) | 2002-09-11 | — | — | EP | disclosed |
| WO-2001034141-A1 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-17 | — | — | WO | disclosed |