Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 7/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 7/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26237102 | 0.74 | SRD5A1 (0.46) | SRD5A1NR1H2NR1H3LMNATDP1 | |
| SCHEMBL4623201 | 0.70 | SRD5A1 (0.40) | SRD5A1NR1H2NR1H3LMNATDP1 | |
| SCHEMBL8048188 | 0.67 | SHBG (0.40) | SRD5A1 | |
| SCHEMBL8038167 | 0.67 | SHBG (0.40) | SRD5A1 | |
| SCHEMBL8048190 | 0.67 | SHBG (0.40) | SRD5A1 | |
| SCHEMBL8050411 | 0.66 | ESR1 (0.50) | SRD5A1LMNACYP3A4 | |
| SCHEMBL7213776 | 0.65 | SHBG (0.55) | NR1H2NR1H3LMNACYP3A4 | |
| SCHEMBL13165160 | 0.64 | LMNA (0.50) | SRD5A1NR1H2NR1H3LMNATDP1 | |
| SCHEMBL20136561 | 0.64 | KDM1A (0.51) | MEN1KMT2ATSHRCYP2C19CYP3A4 | |
| SCHEMBL27183293 | 0.63 | SIGMAR1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002068548-A9 | USE OF ERSS-SELECTIVE LIGANDS FOR REGULATING FERTILITY AND COMPOUNDS USEFUL THEREFORE | SCHERING AG (DE) | 2003-02-20 | — | — | WO | disclosed |