Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15663547 | 0.83 | ALDH1A1 (0.32) | MEN1KMT2AHTTL3MBTL1MCL1 | |
| SCHEMBL16603439 | 0.83 | KDM4E (0.37) | PKMKDM4EMEN1KMT2AEPHX1 | |
| SCHEMBL27413944 | 0.82 | HPGD (0.32) | MEN1KMT2AHTTL3MBTL1 | |
| SCHEMBL11564301 | 0.79 | NPC1 (0.34) | KDM4EMEN1KMT2AEPHX1 | |
| SCHEMBL17943328 | 0.79 | PKM (0.36) | PKMKDM4ETHRBMEN1KMT2A | |
| SCHEMBL17228791 | 0.76 | CTSK (0.43) | MEN1KMT2A | |
| SCHEMBL9867672 | 0.76 | KDM4E (0.31) | KDM4EHTTL3MBTL1 | |
| SCHEMBL25932264 | 0.76 | L3MBTL1 (0.35) | PKMKDM4ETHRBMEN1KMT2A | |
| SCHEMBL7768332 | 0.75 | ALDH1A1 (0.46) | PKMKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL9055813 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020240586-A1 | NOVEL COMPOUNDS FOR INHIBITION OF JANUS KINASE 1 | MANKIND PHARMA LTD. (IN) | 2020-12-03 | — | — | WO | disclosed |
| US-6504046-B1 | Cyclization of nitriles using acids, to form oxazolinone chemical intermediates such as 2-phenyl-4-isopropyl-4-methyl-1,3-oxazol-5-one, used as fungicides | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2003-01-07 | — | — | US | disclosed |
| EP-1092705-A1 | PROCESS FOR THE PREPARATION OF AMIDES | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2001-04-18 | — | — | EP | disclosed |