Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL219445 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL15687582 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL3891354 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL28533969 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL2845079 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL1350178 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL218427 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL1349698 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL9469773 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL27136655 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 19262 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121800548-B | Modified manganous-manganic oxide and application thereof in soft magnetism | Hunan Shuangfu New Material Technology Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-118287112-B | Preparation method and application of cobalt-defect cobalt selenide anchored high-loading Pt single-atom catalyst | Beijing Hydrogen Yi Energy Technology Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-119039596-B | Double-ion battery based on MOF-on-MOF framework anode material and high-concentration double-lithium salt electrolyte | SOUTH CHINA University OF TECHNOLOGY ZHUHAI MODERN INDUSTRIAL INNOVATION INSTITUTE (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-119361274-B | Preparation method of Ni electrode strontium titanate annular piezoresistor | DONGGUAN E-LEO ELECTRONICS Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-116314867-B | High-load cobalt-based monoatomic catalyst applied to oxygen reduction and preparation method thereof | DALIAN UNIVERSITY OF TECHNOLOGY (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122080427-A | Controllable synthesis method of programmable perforated sheet MOF material | — | 2026-05-26 | — | — | CN | claimed |
| CN-122091550-A | High-performance lithium ion battery anode material Si@void@C@NC and preparation method thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-119350131-B | Method for preparing phenolic chemicals by catalytic lignin transfer hydrogenolysis of cobalt-based nitrogen-carbon composite material | SOUTH CHINA UNIVERSITY OF TECHNOLOGY (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122080589-A | Latent curing epoxy resin-based sound absorption and insulation composite material and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122076473-A | Sheet-shaped p-n heterojunction BiOBr/CoWO4Visible light catalytic material and preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| WO-1999022046-A1 | METHOD FOR ELECTROPHORETIC DEPOSITION OF BRAZING MATERIAL | ALLISON ENGINE COMPANY, INC. (US) | 1999-05-06 | — | — | WO | claimed |
| US-5817593-A | RHENIUM, NICKEL, COBALT, BORON AND COPPER, CATALYST SUPPORTS, REDUCTIVE AMINATION | THE DOW CHEMICAL COMPANY (US) | 1998-10-06 | — | — | US | claimed |
| EP-0828558-A1 | CATALYST AND PROCESS FOR PRODUCING AMINES | THE DOW CHEMICAL COMPANY (US) | 1998-03-18 | — | — | EP | claimed |
| US-5627076-A | Method for determination of glycols and polyglycols in drilling fluid filtrates | BAKER HUGHES INCORPORATED (US) | 1997-05-06 | — | — | US | claimed |
| WO-1996038226-A1 | CATALYST AND PROCESS FOR PRODUCING AMINES | THE DOW CHEMICAL COMPANY (US) | 1996-12-05 | — | — | WO | claimed |
| EP-0448117-B1 | Process for producing a catalyst composition for hydrodesulphurization of hydrocarbon oil. | COSMO SOGO KENKYUSHO KK (JP) | 1994-09-28 | — | — | EP | claimed |
| US-5182250-A | Oxides of aluminum and group 6 and group 8 metals | COSMO RESEARCH INSTITUTE (JP) | 1993-01-26 | — | — | US | claimed |
| EP-0448117-A1 | Process for producing a catalyst composition for hydrodesulphurization of hydrocarbon oil. | COSMO RESEARCH INSTITUTE (JP) | 1991-09-25 | — | — | EP | claimed |
| US-4585532-A | Method for using anodes having NiCo2 O4 catalyst for the electrolysis of potassium hydroxide solutions and method of making an anode containing NiCo2 O4 catalyst | INTERNATIONAL FUEL CELLS CORPORATION (US) | 1986-04-29 | — | — | US | claimed |
| EP-0038122-A1 | Forming corrosion-resistant coatings upon the surfaces of metals, especially zinc | AMCHEM PRODUCTS, INC. (US) | 1981-10-21 | — | — | EP | claimed |