Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.56 |
| ▸ | DRD1 | P21728 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.44 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.44 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30679628 | 1.00 | KIF11 (0.56) | KIF11DRD1MAOBKDM1ATRPM2 | |
| Trifluoroacetic Acid SCHEMBL28927044 | 0.91 | KIF11 (0.52) | KIF11DRD1MAOBTRPM2ALDH1A1 | |
| SCHEMBL13221440 | 0.83 | KIF11 (0.56) | KIF11DRD1ALDH1A1POLBL3MBTL1 | |
| SCHEMBL26827704 | 0.82 | MAOB (0.62) | KIF11MAOBKDM1APGRPTPN1 | |
| SCHEMBL1427373 | 0.82 | TRIM24 (0.56) | KIF11DRD1MAOBALDH1A1PTPN1 | |
| SCHEMBL27882694 | 0.82 | MAOB (0.51) | KIF11MAOBKDM1ATRPM2ALDH1A1 | |
| SCHEMBL24106776 | 0.81 | KIF11 (0.67) | KIF11MAOBKDM1AALDH1A1PGR | |
| SCHEMBL16068255 | 0.81 | KIF11 (0.67) | KIF11MAOBKDM1AALDH1A1PGR | |
| SCHEMBL2268468 | 0.81 | KIF11 (0.56) | KIF11DRD1 | |
| SCHEMBL26821704 | 0.81 | KIF11 (0.67) | KIF11MAOBKDM1AALDH1A1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113631548-A | Serotonin 5-HT2B inhibiting compounds | 硕腾服务有限责任公司 | 2021-11-09 | — | — | CN | claimed |
| EP-4570313-A2 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2025-06-18 | — | — | EP | disclosed |
| CN-117430570-A | Rhodamine acetic acid compound, and pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2024-01-23 | — | — | CN | disclosed |
| EP-4219477-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2023-08-02 | — | — | EP | disclosed |
| CN-113631548-A | Serotonin 5-HT2B inhibiting compounds | 硕腾服务有限责任公司 | 2021-11-09 | — | — | CN | disclosed |
| EP-3694840-B1 | PIPERAZINE DERIVATIVES AS MAGL INHIBITORS | HOFFMANN LA ROCHE (CH) | 2021-08-04 | — | — | EP | disclosed |
| US-10626095-B2 | Cyanotriazole compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2020-04-21 | — | — | US | disclosed |
| US-20160229816-A1 | CYANOTRIAZOLE COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2016-08-11 | — | — | US | disclosed |
| US-20100216762-A1 | Agonists and Antagonists of the S1P5 Receptor, and Methods of Use Thereof | ABBOTT LABORATORIES (US) | 2010-08-26 | — | — | US | disclosed |
| US-20100216762-A1 | Agonists and Antagonists of the S1P5 Receptor, and Methods of Use Thereof | ABBOTT LABORATORIES (US) | 2010-08-26 | — | — | US | disclosed |
| EP-1335899-A2 | SUBSTITUTED ALKYLDIAMINES AS INHIBITORS OF PLASMEPSIN OR RELATED PROTEASES | Actelion Pharmaceuticals Ltd. (CH) | 2003-08-20 | — | — | EP | disclosed |
| EP-1322612-A1 | SUBSTITUTED AMINO-AZA-CYCLOALKANES USEFUL AGAINST MALARIA | Actelion Pharmaceuticals Ltd. (CH) | 2003-07-02 | — | — | EP | disclosed |
| WO-2002083641-A2 | AMINO-AZA-CYCLOHEXANES FOR THE TREATMENT OF MALARIA | ACTELION PHARMACEUTICALS LTD. (CH) | 2002-10-24 | — | — | WO | disclosed |
| WO-2002038534-A2 | SUBSTITUTED ALKYLDIAMINES AS INHIBITORS OF PLASMEPSIN OR RELATED PROTEASES | ACTELION PHARMACEUTICALS LTD (CH) | 2002-05-16 | — | — | WO | disclosed |
| WO-2002024649-A1 | SUBSTITUTED AMINO-AZA-CYCLOALKANES USEFUL AGAINST MALARIA | ACTELION PHARMACEUTICALS LTD (CH) | 2002-03-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10626095-B2 | Cyanotriazole compounds | CS, PC, ACAT1 | KIF11 3245/4885DRD1 4556/4885MAOB 3664/4885 |
| US-20100216762-A1 | Agonists and Antagonists of the S1P5 Receptor, and Methods of Use Thereof | S1PR5, LPAR5, S1PR1 | KIF11 3238/4885DRD1 821/4885MAOB 2578/4885 |
| US-20160229816-A1 | CYANOTRIAZOLE COMPOUNDS | CS, PC, ACAT1 | KIF11 3245/4885DRD1 4556/4885MAOB 3664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.