Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 3/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | IDH1 | O75874 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ATP1A1 | P05023 | 2/20 | 0.34 |
| ▸ | ATP1B1 | P05026 | 2/20 | 0.34 |
| ▸ | ATP1A3 | P13637 | 2/20 | 0.34 |
| ▸ | ATP1B2 | P14415 | 2/20 | 0.34 |
| ▸ | ATP1A2 | P50993 | 2/20 | 0.34 |
| ▸ | ATP1B3 | P54709 | 2/20 | 0.34 |
| ▸ | FXYD2 | P54710 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7215726 | 0.87 | OPRD1 (0.37) | MDM2IDO1KMT2AMEN1HSP90AA1 | |
| SCHEMBL7216134 | 0.85 | ATP1A1 (0.48) | OPRD1OPRK1P2RX3ATP1A1ATP1B1 | |
| SCHEMBL7216328 | 0.80 | GPR39 (0.43) | KMT2AMEN1OPRD1OPRK1 | |
| SCHEMBL7217985 | 0.77 | ATP1A1 (0.48) | IDH1KMT2AMEN1OPRD1OPRK1 | |
| SCHEMBL7221629 | 0.76 | ATP1A1 (0.51) | KMT2AHSP90AA1OPRD1OPRK1RAB9A | |
| SCHEMBL7222405 | 0.74 | SMN1; SMN2 (0.46) | KMT2APOLBOPRD1OPRK1RAB9A | |
| SCHEMBL7215523 | 0.69 | SOS1 (0.37) | SOS1MDM2IDH1KMT2AMEN1 | |
| SCHEMBL7216242 | 0.68 | ATP1A1 (0.70) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL7222468 | 0.68 | OPRD1 (0.39) | KMT2AMEN1OPRD1OPRK1ATP1A1 | |
| SCHEMBL7215976 | 0.66 | GAA (0.44) | KMT2AMEN1POLBOPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596739-B2 | Anticarcinogenic agents, cardiovascular disorders and antiinflammatory agents | THE PROCTER & GAMBLE COMPANY | 2003-07-22 | — | — | US | claimed |