Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.37 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.37 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.37 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.37 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.37 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.37 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.37 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | IDO1 | P14902 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP27B1 | O15528 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7215522 | 0.87 | SOS1 (0.37) | OPRD1OPRK1ATP1A1ATP1B1ATP1A3 | |
| SCHEMBL7221629 | 0.86 | ATP1A1 (0.51) | OPRD1OPRK1ATP1A1ATP1B1ATP1A3 | |
| SCHEMBL7216328 | 0.79 | GPR39 (0.43) | OPRD1OPRK1KMT2AMEN1TP53 | |
| SCHEMBL7222468 | 0.78 | OPRD1 (0.39) | OPRD1OPRK1ATP1A1ATP1B1ATP1A3 | |
| SCHEMBL7216134 | 0.77 | ATP1A1 (0.48) | OPRD1OPRK1ATP1A1ATP1B1ATP1A3 | |
| SCHEMBL7222405 | 0.74 | SMN1; SMN2 (0.46) | OPRD1OPRK1RAB9AKMT2ATP53 | |
| SCHEMBL7215731 | 0.71 | KMT2A (0.35) | RAB9AKMT2AIDO1MEN1LMNA | |
| SCHEMBL7216362 | 0.70 | ATP1A1 (0.72) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL7217985 | 0.68 | ATP1A1 (0.48) | OPRD1OPRK1ATP1A1ATP1B1ATP1A3 | |
| SCHEMBL7215736 | 0.67 | ATP1A1 (0.36) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596739-B2 | Anticarcinogenic agents, cardiovascular disorders and antiinflammatory agents | THE PROCTER & GAMBLE COMPANY | 2003-07-22 | — | — | US | claimed |