Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP1A1 | P05023 | 7/20 | 0.48 |
| ▸ | ATP1B1 | P05026 | 7/20 | 0.48 |
| ▸ | ATP1A3 | P13637 | 7/20 | 0.48 |
| ▸ | ATP1B2 | P14415 | 7/20 | 0.48 |
| ▸ | ATP1A2 | P50993 | 7/20 | 0.48 |
| ▸ | ATP1B3 | P54709 | 7/20 | 0.48 |
| ▸ | FXYD2 | P54710 | 7/20 | 0.48 |
| ▸ | ATP1A4 | Q13733 | 7/20 | 0.48 |
| ▸ | PDE1C | Q14123 | 7/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.35 |
| ▸ | PDE9A | O76083 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7217985 | 0.89 | ATP1A1 (0.48) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL7221629 | 0.86 | ATP1A1 (0.51) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL7215522 | 0.85 | SOS1 (0.37) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL7222405 | 0.80 | SMN1; SMN2 (0.46) | OPRD1OPRK1 | |
| SCHEMBL7215726 | 0.77 | OPRD1 (0.37) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL7222468 | 0.75 | OPRD1 (0.39) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL7216328 | 0.74 | GPR39 (0.43) | OPRD1OPRK1PDE9A | |
| SCHEMBL7215976 | 0.69 | GAA (0.44) | OPRD1OPRK1 | |
| SCHEMBL7216137 | 0.67 | PDE9A (0.37) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL7217993 | 0.65 | ATP1A1 (1.00) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596739-B2 | Anticarcinogenic agents, cardiovascular disorders and antiinflammatory agents | THE PROCTER & GAMBLE COMPANY | 2003-07-22 | — | — | US | claimed |