Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
| ▸ | BCAT1 | P54687 | 2/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.50 |
| ▸ | IL1RN | P18510 | 1/20 | 0.50 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10448678 | 0.81 | BCAT1 (0.47) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL8908871 | 0.78 | KDM4E (0.36) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL27529113 | 0.78 | CA1 (0.55) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL8909408 | 0.77 | KDM4E (0.38) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL16177890 | 0.77 | PSIP1 (0.48) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL10954659 | 0.76 | PTGES (0.51) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL9023670 | 0.75 | PTGES (0.51) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL10415530 | 0.74 | BCAT1 (0.49) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL10449151 | 0.74 | KEAP1 (0.47) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL15512616 | 0.74 | BCAT1 (0.53) | CA1CA2MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101589043-A | Purine derivatives | PALAU PHARMA SA (ES) | 2009-11-25 | — | — | CN | disclosed |
| CN-1104877-C | tooth adhesive | HERAEUS KULZER GMBH (DE) | 2003-04-09 | — | — | CN | disclosed |
| US-6541503-B2 | Preventing chemotherapy induced alopecia. | SMITHKLINE BEECHAM CORPORATION | 2003-04-01 | — | — | US | disclosed |
| CN-1234733-A | Dental adhesive | HERAEUS KULZER GMBH (DE) | 1999-11-10 | — | — | CN | disclosed |
| US-5921779-A | CONTAINING GLYCEROL DI(METH)ACRYLATE | HERAEUS KULZER GMBH & CO. KG (DE) | 1999-07-13 | — | — | US | disclosed |
| US-5808104-A | DENTAL FILLINGS WITH HIGH BONDING STRENGTH | HERAEUS KULZER GMBH (DE) | 1998-09-15 | — | — | US | disclosed |
| US-5760101-A | AN OLIGOMERIC CONDENSATION PRODUCT OR A POLYESTERS ADHESIVE FOR TEETH FILLING | HERAEUS KULZER GMBH (DE) | 1998-06-02 | — | — | US | disclosed |