Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.51 |
| ▸ | BCAT1 | P54687 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7215570 | 0.75 | CA1 (0.52) | PTGESBCAT1CA1CA2MMP1 | |
| SCHEMBL15512616 | 0.71 | BCAT1 (0.53) | PTGESBCAT1CA1CA2MMP1 | |
| SCHEMBL11514440 | 0.71 | KMT2A (0.51) | PTGESALDH1A1HTTGAAKMT2A | |
| SCHEMBL16177890 | 0.71 | PSIP1 (0.48) | BCAT1CA1CA2MMP1MMP2 | |
| SCHEMBL3651088 | 0.71 | EGFR (0.54) | BCAT1CA1CA2MMP1MMP2 | |
| SCHEMBL10448678 | 0.71 | BCAT1 (0.47) | BCAT1CA1CA2MMP1MMP2 | |
| SCHEMBL11513730 | 0.68 | MEN1 (0.72) | BCAT1ALDH1A1HTTGAAKMT2A | |
| SCHEMBL28204994 | 0.68 | CA1 (0.48) | PTGESBCAT1CA1CA2MMP1 | |
| SCHEMBL366135 | 0.67 | CA2 (0.52) | BCAT1CA1CA2MMP1MMP2 | |
| SCHEMBL11512832 | 0.67 | ALDH1A1 (0.44) | PTGESALDH1A1GAAKMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706518-A1 | ACYLATED AMINOPHENYL UREA COMPOUNDS, THEIR PREPARATION AND THEIR USE AS HERBICIDES AND PLANT-GROWTH REGULATORS | Hoechst Schering AgrEvo GmbH (DE) | 1996-04-17 | — | — | EP | disclosed |
| WO-1995001344-A1 | ACYLATED AMINOPHENYL UREA COMPOUNDS, THEIR PREPARATION AND THEIR USE AS HERBICIDES AND PLANT-GROWTH REGULATORS | HOECHST SCHERING AGREVO GMBH (DE) | 1995-01-12 | — | — | WO | disclosed |