SCHEMBL7216154

SCHEMBL7216154

CC1=NC(C)(C(C)C)C(=O)O1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8627083 0.72
SCHEMBL7219131 0.68 NOTUM (0.35)
SCHEMBL8741970 0.66 SLC7A5 (0.31)
SCHEMBL8741974 0.66 SLC7A5 (0.31)
SCHEMBL8741969 0.66 SLC7A5 (0.31)
SCHEMBL7214039 0.64 ADRB2 (0.33)
SCHEMBL9265005 0.62 TSHR (0.36)
SCHEMBL5933648 0.62 TSHR (0.36)
SCHEMBL7662936 0.61 MMP2 (0.37)
SCHEMBL18560362 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0303863-A2 Benzenesulfonyl carboxamide compounds, intermediate compounds and methods of preparation thereof and use of said compounds and intermediate compounds as herbicidal agents AMERICAN CYANAMID COMPANY (US) 1989-02-22 EP claimed
US-6504046-B1 Cyclization of nitriles using acids, to form oxazolinone chemical intermediates such as 2-phenyl-4-isopropyl-4-methyl-1,3-oxazol-5-one, used as fungicides IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 2003-01-07 US disclosed
EP-1092705-A1 PROCESS FOR THE PREPARATION OF AMIDES IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) 2001-04-18 EP disclosed
US-5391757-A Benzenesulfonyl carboxamide compounds intermediate compounds and methods of preparation thereof and use of said compounds and intermediate compounds as herbicidal agents AMERICAN CYANAMID COMPANY (US) 1995-02-21 US disclosed
US-5338883-A Benzenesulfonyl carboxamide compounds intermediate compounds and methods of preparation thereof and use of said compounds and intermediate compounds as herbicidal agents AMERICAN CYANAMID COMPANY (US) 1994-08-16 US disclosed
US-5252539-A Benzenesulfonyl carboxamide compounds intermediate compounds and method of preparation thereof and use of said compounds and intermediate compounds as herbicidal agents AMERICAN CYANAMID COMPANY (US) 1993-10-12 US disclosed
US-5120854-A Benzenesulfonyl carboxamide compounds and intermediate compounds AMERICAN CYANAMID COMPANY (US) 1992-06-09 US disclosed
US-4992094-A Herbicides AMERICAN CYANAMID COMPANY (US) 1991-02-12 US disclosed
US-4883914-A Benzenesulfonyl carboxamide compounds useful as herbicidal agents AMERICAN CYANAMID COMPANY (US) 1989-11-28 US disclosed
EP-0303863-A2 Benzenesulfonyl carboxamide compounds, intermediate compounds and methods of preparation thereof and use of said compounds and intermediate compounds as herbicidal agents AMERICAN CYANAMID COMPANY (US) 1989-02-22 EP disclosed