Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GPR39 | O43194 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PDE9A | O76083 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.36 |
| ▸ | GPR18 | Q14330 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | VDR | P11473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7222413 | 0.85 | SMN1; SMN2 (0.49) | LMNAGPR39NPSR1TP53MAPT | |
| SCHEMBL7215528 | 0.77 | ATP1A1 (0.41) | LMNANPSR1TP53MAPTHTT | |
| SCHEMBL7215736 | 0.77 | ATP1A1 (0.36) | — | |
| SCHEMBL7215980 | 0.76 | KDM4E (0.46) | LMNATP53MAPTHTTALDH1A1 | |
| SCHEMBL7222082 | 0.76 | GPR39 (0.41) | LMNAGPR39MAPTSLC2A1CDC7 | |
| SCHEMBL7216143 | 0.73 | ATP1A1 (0.51) | — | |
| SCHEMBL7221640 | 0.72 | ATP1A1 (0.50) | — | |
| SCHEMBL7222080 | 0.70 | LMNA (0.48) | LMNAGPR39TP53MAPTSLC2A1 | |
| SCHEMBL7229228 | 0.69 | RAB9A (0.55) | NPSR1MAPTALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL7222175 | 0.68 | GAA (0.62) | LMNATP53MAPTHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596739-B2 | Anticarcinogenic agents, cardiovascular disorders and antiinflammatory agents | THE PROCTER & GAMBLE COMPANY | 2003-07-22 | — | — | US | claimed |