Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP1A1 | P05023 | 2/20 | 0.36 |
| ▸ | ATP1B1 | P05026 | 2/20 | 0.36 |
| ▸ | ATP1A3 | P13637 | 2/20 | 0.36 |
| ▸ | ATP1B2 | P14415 | 2/20 | 0.36 |
| ▸ | ATP1A2 | P50993 | 2/20 | 0.36 |
| ▸ | ATP1B3 | P54709 | 2/20 | 0.36 |
| ▸ | FXYD2 | P54710 | 2/20 | 0.36 |
| ▸ | ATP1A4 | Q13733 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 4/20 | 0.34 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | CTSA | P10619 | 2/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7215528 | 0.86 | ATP1A1 (0.41) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL7221640 | 0.86 | ATP1A1 (0.50) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL7222472 | 0.78 | PSEN1 (0.39) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL7216336 | 0.77 | LMNA (0.45) | — | |
| SCHEMBL7216143 | 0.76 | ATP1A1 (0.51) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL7222413 | 0.73 | SMN1; SMN2 (0.49) | RAB9A | |
| SCHEMBL7216362 | 0.70 | ATP1A1 (0.72) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL7217988 | 0.68 | ATP1A1 (0.51) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL7215726 | 0.67 | OPRD1 (0.37) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL7229228 | 0.66 | RAB9A (0.55) | RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596739-B2 | Anticarcinogenic agents, cardiovascular disorders and antiinflammatory agents | THE PROCTER & GAMBLE COMPANY | 2003-07-22 | — | — | US | claimed |