SCHEMBL7216633

SCHEMBL7216633

CC(CCC(C)(C)C(=O)O)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ACACB O00763 1/20 0.53
ACACA Q13085 1/20 0.53
GABRR1 P24046 2/20 0.48
CYP1A2 P05177 1/20 0.48
BLM P54132 1/20 0.42
ACLY P53396 1/20 0.41
ACE2 Q9BYF1 1/20 0.39
LTA4H P09960 1/20 0.38
FOLH1 Q04609 2/20 0.33
NAALAD2 Q9Y3Q0 2/20 0.33
ENPEP Q07075 2/20 0.33
MME P08473 1/20 0.33
MMEL1 Q495T6 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15022119 0.89 ACACB (0.62) ACACBACACAGABRR1CYP1A2BLM
SCHEMBL3259070 0.85 ACACB (0.69) ACACBACACAGABRR1CYP1A2BLM
SCHEMBL4653627 0.82 ACACB (0.46) ACACBACACAGABRR1CYP1A2BLM
SCHEMBL5970903 0.82 GABRR1 (0.48) ACACBACACAGABRR1CYP1A2BLM
SCHEMBL8441142 0.82 BLM (0.49) ACACBACACAGABRR1CYP1A2BLM
SCHEMBL3753790 0.81 GABRR1 (0.52) ACACBACACAGABRR1CYP1A2BLM
SCHEMBL2718566 0.81 ACACB (0.52) ACACBACACABLMACLY
SCHEMBL6196497 0.81 ACACB (0.69) ACACBACACAGABRR1CYP1A2ACLY
SCHEMBL27286922 0.81 GABRR1 (0.52) ACACBACACAGABRR1CYP1A2BLM
SCHEMBL10595182 0.79 GABRR1 (0.42) ACACBACACAGABRR1CYP1A2BLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150259311-A1 METHOD OF PRODUCING LACTONE FROM HYDROXYCARBOXYLIC ACID OR DICARBOXYLIC ACID IN AQUEOUS SOLUTION SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-09-17 US claimed
US-20130204015-A1 PROCESS FOR PREPARING A LACTONE RHODIA OPERATIONS (FR) 2013-08-08 US claimed
US-5856581-A DECARBOXYLATING/CYCLIZING A DICARBOXYLIC ACID, IN LIQUID PHASE, IN THE PRESENCE OF A CATALYTICALLY EFFECTIVE AMOUNT OF A METAL OR COMPOUND COMPOUND THEREOF SELECTED FROM AMONG BORON, ALUMINUM, GALLIUM, INDIUM, THALLIUM, TIN, ANTIMONY, RHONE-POULENC CHIMIE (FR) 1999-01-05 US claimed
EP-0626364-B1 Process for the preparation of a cyclic ketone RHONE POULENC CHIMIE (FR) 1998-04-08 EP claimed
EP-0626363-B1 Process for the préparation of a cyclic ketone RHONE POULENC CHIMIE (FR) 1998-03-04 EP claimed
US-5600013-A CATALYTIC CARBOXYLATION AND CYCLIZATION OF DICARBOXYLIC ACIDS RHONE-POULENC CHIMIE (FR) 1997-02-04 US claimed
US-12534568-B2 Polyester carbonates consisting of different diols in a defined ratio COVESTRO DEUTSCHLAND AG (DE) 2026-01-27 US disclosed
US-12516152-B2 Polyester carbonates having a defined proportion of ester groups COVESTRO DEUTSCHLAND AG (DE) 2026-01-06 US disclosed
US-12473397-B2 Polyester carbonates from aliphatic diacids and aliphatic diols, and process for the production thereof COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2025-11-18 US disclosed
WO-2025068164-A1 SEQUENTIAL PROCESS FOR PRODUCING POLYESTER CARBONATES CONTAINING 1,4:3,6-DIANHYDROHEXITOL COVESTRO DEUTSCHLAND AG (DE) 2025-04-03 WO disclosed
EP-4168468-B1 POLYESTER CARBONATES MADE FROM CYCLOALIPHATIC DIACIDS, 1,4 : 3,6-DIANHYDRO-HEXITOLE AND A FURTHER ALIPHATIC DIHYDROXY COMPOUND COVESTRO DEUTSCHLAND AG (DE) 2025-04-02 EP disclosed
EP-4168470-B1 POLYESTER CARBONATES HAVING A DEFINED CONTENT OF ESTER GROUPS COVESTRO DEUTSCHLAND AG (DE) 2024-04-24 EP disclosed
US-20230340190-A1 Polyester Carbonates From Cycloaliphatic Diacids, 1,4:3,6-Dianhydrohexitol and a Further Aliphatic Dihydroxy Compound COVESTRO DEUTSCHLAND AG (DE) 2023-10-26 US disclosed
EP-2610248-A1 METHOD FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE BY MEANS OF COUPLING METHOD USING A PALLADIUM COMPOUND Teijin Pharma Limited (JP) 2013-07-03 EP disclosed
US-20130158272-A1 METHOD FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE BY MEANS OF COUPLING METHOD USING PALLADIUM COMPOUND TEIJIN PHARMA LIMITED (JP) 2013-06-20 US disclosed
CN-103068807-A Method for producing phenyl-substituted heterocyclic derivative by means of coupling method using a palladium compound TEIJIN PHARMA LTD 2013-04-24 CN disclosed
US-6570028-B1 Reacting a diacid with epi(chloro or bromo)hydrin; using Group 1a hydroxide catalyst; distillation RESOLUTION PERFORMANCE PRODUCTS LLC 2003-05-27 US disclosed
WO-2001062752-A1 PROCESS FOR THE PREPARATION OF GLYCIDYLESTERS OF BRANCHED CARBOXYLIC ACIDS RESOLUTION RESEARCH NEDERLAND B.V. (NL) 2001-08-30 WO disclosed
US-5856581-A DECARBOXYLATING/CYCLIZING A DICARBOXYLIC ACID, IN LIQUID PHASE, IN THE PRESENCE OF A CATALYTICALLY EFFECTIVE AMOUNT OF A METAL OR COMPOUND COMPOUND THEREOF SELECTED FROM AMONG BORON, ALUMINUM, GALLIUM, INDIUM, THALLIUM, TIN, ANTIMONY, RHONE-POULENC CHIMIE (FR) 1999-01-05 US disclosed
US-5600013-A CATALYTIC CARBOXYLATION AND CYCLIZATION OF DICARBOXYLIC ACIDS RHONE-POULENC CHIMIE (FR) 1997-02-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130204015-A1 PROCESS FOR PREPARING A LACTONE HSD17B7, HSD17B3, RPS3 ACACB 1187/4885ACACA 686/4885GABRR1 753/4885
US-20130158272-A1 METHOD FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE BY MEANS OF COUPLING METHOD USING PALLADIUM COMPOUND XDH, AOC1, PAH ACACB 1851/4885ACACA 1266/4885GABRR1 3535/4885
US-12534568-B2 Polyester carbonates consisting of different diols in a defined ratio HSD11B2, HSD11B1, HSD3B1 ACACB 179/4885ACACA 170/4885GABRR1 1461/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.