SCHEMBL7216707

SCHEMBL7216707

Nc1cc(C(=O)O)cnc1N

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
KDM4E B2RXH2 3/20 0.50
GABRP O00591 2/20 0.50
GABRD O14764 2/20 0.50
GABRA1 P14867 2/20 0.50
GABRB1 P18505 2/20 0.50
GABRG2 P18507 2/20 0.50
GABRB3 P28472 2/20 0.50
GABRA5 P31644 2/20 0.50
GABRA3 P34903 2/20 0.50
GABRA2 P47869 2/20 0.50
GABRB2 P47870 2/20 0.50
GABRA4 P48169 2/20 0.50
GABRE P78334 2/20 0.50
GABRA6 Q16445 2/20 0.50
GABRG1 Q8N1C3 2/20 0.50
GABRG3 Q99928 2/20 0.50
GABRQ Q9UN88 2/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30884164 1.00 ALDH1A1 (0.50) ALDH1A1KDM4EGABRPGABRDGABRA1
SCHEMBL2087026 0.83 NNMT (0.50) MAP4K4
SCHEMBL19857474 0.81 ALDH1A1 (0.48) ALDH1A1KDM4EGABRPGABRDGABRA1
SCHEMBL2805912 0.81 GABRP (0.48) ALDH1A1KDM4EGABRPGABRDGABRA1
SCHEMBL29415435 0.81 GABRP (0.48) ALDH1A1KDM4EGABRPGABRDGABRA1
SCHEMBL7599288 0.79 KMT2A (0.52) ALDH1A1KDM4EGABRPGABRDGABRA1
SCHEMBL8061081 0.79 GABRP (0.47) ALDH1A1KDM4EGABRPGABRDGABRA1
SCHEMBL21912461 0.79 GABRP (0.47) ALDH1A1KDM4EGABRPGABRDGABRA1
SCHEMBL7356328 0.79 KDM4E (0.47) ALDH1A1KDM4EGABRPGABRDGABRA1
SCHEMBL11188300 0.79 HCAR2 (0.47) ALDH1A1KDM4EGABRPGABRDGABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118126325-A Low-temperature-cured alkali-soluble photosensitive resin and preparation method thereof 深圳先进电子材料国际创新研究院 2024-06-04 CN claimed
CN-117757432-A High-suspension grinding fluid suitable for large-size silicon wafer, preparation method and application 江苏奥首材料科技有限公司 2024-03-26 CN claimed
CN-115960352-B Photosensitive polyimide precursor resin, preparation method thereof and photosensitive resin composition 深圳市道尔顿电子材料股份有限公司 2024-07-05 CN disclosed
CN-118126325-A Low-temperature-cured alkali-soluble photosensitive resin and preparation method thereof 深圳先进电子材料国际创新研究院 2024-06-04 CN disclosed
CN-117757432-A High-suspension grinding fluid suitable for large-size silicon wafer, preparation method and application 江苏奥首材料科技有限公司 2024-03-26 CN disclosed
CN-115960352-A Photosensitive polyimide precursor resin, preparation method thereof and photosensitive resin composition 深圳市道尔顿电子材料有限公司 2023-04-14 CN disclosed
CN-109535402-B Preparation method of polyarylate based on 2- (4-hydroxyphenyl) -5-carboxypyridoimidazole 宁波聚嘉新材料科技有限公司 2021-10-12 CN disclosed
CN-110317324-B Preparation method of polyarylate based on 2- (4-hydroxy-3-methoxyphenyl) -5-carboxypyridoimidazole 浙江甬仑聚嘉新材料有限公司 2021-03-02 CN disclosed
CN-110317324-A The preparation method of polyarylate of the one kind based on 2- (4- hydroxy 3-methoxybenzene base) -5- carboxyl pyridine and imidazoles 浙江甬仑聚嘉新材料有限公司 2019-10-11 CN disclosed
CN-109535402-A The preparation method of polyarylate of the one kind based on 2- (4- hydroxy phenyl) -5- carboxyl pyridine and imidazoles 宁波聚嘉新材料科技有限公司 2019-03-29 CN disclosed
CN-101203518-B Fluorene derivative, composition containing the same and use thereof AVENTIS PHARMA SA 2013-07-24 CN disclosed
CN-101203518-A Novel fluorene derivatives, compositions containing same and uses thereof AVENTIS PHARMA SA (FR) 2008-06-18 CN disclosed
US-6610692-B1 Anticoagulants MERCK & CO., INC. 2003-08-26 US disclosed
US-6610701-B2 For therapy and prophylaxis of blood coagulation and cardiovascular disorders MERCK & CO., INC. 2003-08-26 US disclosed
US-20020193398-A1 Thrombin inhibitors MERCK & CO., INC. 2002-12-19 US disclosed
WO-2002064211-A1 THROMBIN INHIBITORS MERCK & CO., INC. (US) 2002-08-22 WO disclosed
EP-1124822-A4 THROMBIN INHIBITORS MERCK & CO INC (US) 2002-04-03 EP disclosed
EP-1124822-A1 THROMBIN INHIBITORS Merck & Co., Inc. (US) 2001-08-22 EP disclosed
WO-2000026211-A1 THROMBIN INHIBITORS MERCK & CO., INC. (US) 2000-05-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020193398-A1 Thrombin inhibitors F2, F3, TFPI ALDH1A1 3527/4885KDM4E 3146/4885GABRP 3819/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.