Remogliflozin Etabonate

Remogliflozin Etabonate

SCHEMBL721678

CCOC(=O)OC[C@H]1O[C@@H](Oc2nn(C(C)C)c(C)c2Cc2ccc(OC(C)C)cc2)[C@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

SLC5A2

The experimentally established mechanism targets of Remogliflozin Etabonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SLC5A2 known ✓ P31639 20/20 1.00
SLC5A1 P13866 18/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Remogliflozin Etabonate SCHEMBL16421581 1.00 SLC5A2 (1.00) SLC5A2SLC5A1
Remogliflozin Etabonate SCHEMBL15168697 1.00 SLC5A2 (1.00) SLC5A2SLC5A1
Remogliflozin Etabonate SCHEMBL10081649 1.00 SLC5A2 (1.00) SLC5A2SLC5A1
Remogliflozin Etabonate SCHEMBL18432846 1.00 SLC5A2 (1.00) SLC5A2SLC5A1
Remogliflozin Etabonate SCHEMBL10066609 1.00 SLC5A2 (1.00) SLC5A2SLC5A1
Remogliflozin Etabonate SCHEMBL23072082 1.00 SLC5A2 (1.00) SLC5A2SLC5A1
Remogliflozin Etabonate SCHEMBL17034638 1.00 SLC5A2 (1.00) SLC5A2SLC5A1
SCHEMBL14634764 0.98 SLC5A2 (0.95) SLC5A2SLC5A1
SCHEMBL14634761 0.98 SLC5A2 (0.95) SLC5A2SLC5A1
SCHEMBL877233 0.98 SLC5A2 (0.95) SLC5A2SLC5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4727528-A1 A PHARMACEUTICAL FORMULATION COMPRISING LINAGLIPTIN, METFORMIN AND A SGLT-2 INHIBITOR Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi (TR) 2026-04-22 EP claimed
EP-4719430-A1 COMBINATION TREATMENT AND/OR PREVENTION OF RENAL DISEASES AND/OR HYPERTENSION IN NON-HUMAN MAMMALS COMPRISING ONE OR MORE SGLT-2 INHIBITORS AND TELMISARTAN Boehringer Ingelheim Vetmedica GmbH (DE) 2026-04-08 EP claimed
EP-4719429-A1 COMBINATION TREATMENT AND/OR PREVENTION OF CARDIAC DISEASES IN NON-HUMAN MAMMALS COMPRISING ONE OR MORE SGLT-2 INHIBITORS AND PIMOBENDAN AND/OR TELMISARTAN Boehringer Ingelheim Vetmedica GmbH (DE) 2026-04-08 EP claimed
US-20260069559-A1 COMBINATIONS OF RXFP1 MODULATORS AND SGLT2 INHIBITORS ASTRAZENECA AB (SE) 2026-03-12 US claimed
EP-4271674-B9 CARBOXY-BENZIMIDAZOLE GLP-1R MODULATING COMPOUNDS GILEAD SCIENCES INC (US) 2026-03-11 EP claimed
EP-4701626-A1 AMORPHOUS OBICETRAPIB AND SGLT2 INHIBITOR COMBINATION NewAmsterdam Pharma B.V. (NL) 2026-03-04 EP claimed
EP-4691554-A2 GLP-1R MODULATING COMPOUNDS Gilead Sciences, Inc. (US) 2026-02-11 EP claimed
US-20260014164-A1 COMBINATION THERAPY FOR PI3K-ASSOCIATED DISEASE OR DISORDER UNIV CORNELL (US) 2026-01-15 US claimed
EP-4676494-A1 SYSTEMS FOR DELIVERY OF LIQUID PHARMACEUTICAL COMPOSITIONS IN PARTICULAR COMPRISING ONE OR MORE SGLT-2 INHIBITOR(S) Boehringer Ingelheim Vetmedica GmbH (DE) 2026-01-14 EP claimed
US-12497382-B2 GLP-1R modulating compounds GILEAD SCIENCES, INC. (US) 2025-12-16 US claimed
US-20090093419-A1 GLUCOPYRANOSYLOXYPYRAZOLE DERIVATIVES AND USE THEREOF IN MEDICINES KISSEI PHARMACEUTICAL CO. LTD. (JP) 2009-04-09 US claimed
US-7465713-B2 Glucopyranosyloxypyrazole derivatives and use thereof in medicines KISSEI PHARMACEUTICAL CO., LTD. (JP) 2008-12-16 US claimed
US-7429568-B2 Antidiabetic agents; human SGLT2 (sodium ion / glucose cotransporter 2) inhibitors; hyperglycemia, obesity; 3-(6-O-ethoxycarbonyl- beta -D-glucopyranosyloxy)-4-[(4-isopropoxyphenyl)methyl]-1-isopropyl-5-methylpyrazole KISSEI PHARMACEUTICAL CO., LTD. (JP) 2008-09-30 US claimed
US-7393838-B2 Glucopyranosyloxypyrazole derivatives and use thereof in medicines KISSEI PHARMACEUTICAL CO., LTD. (JP) 2008-07-01 US claimed
EP-1912656-A2 METHODS FOR PREVENTING AND TREATING METABOLIC DISORDERS AND NEW PYRAZOLE-O-GLYCOSIDE DERIVATIVES Boehringer Ingelheim International GmbH (DE) 2008-04-23 EP claimed
US-20070072813-A1 Methods for preventing and treating metabolic disorders and new pyrazole-O-glycoside derivatives AJINOMOTO CO., INC. (JP) 2007-03-29 US claimed
WO-2007014895-A2 METHODS FOR PREVENTING AND TREATING METABOLIC DISORDERS AND NEW PYRAZOLE-O-GLYCOSIDE DERIVATIVES BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2007-02-08 WO claimed
US-7084123-B2 Glucopyranosyloxypyrazole derivatives and use thereof in medicines KISSEI PHARMACEUTICAL CO., LTD. (JP) 2006-08-01 US claimed
US-20040063646-A1 Glucopyranosyloxypyrazole derivatives and use thereof in medicines KISSEI PHARMACEUTICAL CO., LTD. (JP) 2004-04-01 US claimed
EP-1354888-A1 GLUCOPYRANOSYLOXYPYRAZOLE DERIVATIVES AND USE THEREOF IN MEDICINES Kissei Pharmaceutical Co., Ltd. (JP) 2003-10-22 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260069559-A1 COMBINATIONS OF RXFP1 MODULATORS AND SGLT2 INHIBITORS RXFP1, RXFP2, RXFP4 SLC5A2 6/4885SLC5A1 5/4885
US-20070072813-A1 Methods for preventing and treating metabolic disorders and new pyrazole-O-glycoside derivatives IAPP, G6PC1, GPR119 SLC5A2 6/4885SLC5A1 4/4885
US-20090093419-A1 GLUCOPYRANOSYLOXYPYRAZOLE DERIVATIVES AND USE THEREOF IN MEDICINES SLC5A2, SLC5A1, SLC2A4 SLC5A2 1/4885SLC5A1 2/4885
US-20040063646-A1 Glucopyranosyloxypyrazole derivatives and use thereof in medicines SLC5A2, SLC5A1, UGGT1 SLC5A2 1/4885SLC5A1 2/4885
US-20260014164-A1 COMBINATION THERAPY FOR PI3K-ASSOCIATED DISEASE OR DISORDER MTOR, IRS1, IGF1R SLC5A2 112/4885SLC5A1 81/4885
US-12497382-B2 GLP-1R modulating compounds GLP1R, GIPR, GPR119 SLC5A2 37/4885SLC5A1 27/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.