SCHEMBL7217067

SCHEMBL7217067

CCCCC(C)C(=O)OC(CC(C)C)CC(C)C

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CTSK P43235 5/20 0.53
CA1 P00915 3/20 0.41
CA2 P00918 2/20 0.39
FAAH O00519 1/20 0.36
FDPS P14324 1/20 0.35
LMNA P02545 3/20 0.35
ALDH1A1 P00352 1/20 0.35
CYP3A4 P08684 1/20 0.35
TSHR P16473 1/20 0.35
ATM Q13315 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
MAPK1 P28482 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7224932 0.95 CA1 (0.48) CTSKCA1FAAHLMNAALDH1A1
SCHEMBL7225044 0.93 CA1 (0.47) CTSKCA1FAAHLMNAALDH1A1
SCHEMBL7217921 0.89 CTSK (0.44) CTSKCA1FAAHFDPSALDH1A1
SCHEMBL7224543 0.82 CA2 (0.58) CTSKCA1CA2CYP3A4TSHR
SCHEMBL7217575 0.80 CTSK (0.39) CTSK
SCHEMBL6900329 0.80 LMNA (0.48) CTSKCA1CA2FAAHFDPS
SCHEMBL7216971 0.80 CTSK (0.38) CTSKALDH1A1TSHR
SCHEMBL23586830 0.79 CTSK (0.46) CTSKCA1CA2FAAHFDPS
SCHEMBL2897891 0.79 CA1 (0.52) CA1FAAHLMNAALDH1A1
SCHEMBL19591868 0.79 CA1 (0.39) CTSKCA1CA2FAAHFDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6667285-B1 Branched-chain carboxylic acid monoalkyl ester with outstanding hydrolytic stability NEW JAPAN CHEMICAL CO., LTD. (JP) 2003-12-23 US disclosed
EP-1225213-A1 LUBRICATING OIL FOR REFRIGERATOR, HYDRAULIC FLUID COMPOSITION FOR REFRIGERATOR AND METHOD FOR LUBRICATION OF REFRIGERATOR NEW JAPAN CHEMICAL CO.,LTD. (JP) 2002-07-24 EP disclosed