Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 2/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4243309 | 0.87 | KIF11 (0.48) | CREBBPCA1CA2CA12CA7 | |
| SCHEMBL9741709 | 0.83 | HCRTR1 (0.52) | CA1CA2CA12CA7CA9 | |
| SCHEMBL5540470 | 0.71 | CA12 (0.50) | CA1CA2CA12CA7CA9 | |
| SCHEMBL28063129 | 0.70 | KIF11 (0.70) | CREBBPCA1CA2CA12CA7 | |
| SCHEMBL310518 | 0.70 | ALDH1A1 (0.47) | CA1CA2CA12CA7CA9 | |
| SCHEMBL29377304 | 0.70 | TUBB4A (0.58) | NPC1RAB9AMAPT | |
| SCHEMBL20504955 | 0.70 | PSMB8 (0.51) | CREBBPCA1CA2CA12CA7 | |
| SCHEMBL103794 | 0.70 | TUBB4A (0.58) | NPC1RAB9AMAPT | |
| SCHEMBL4672838 | 0.70 | CA1 (0.57) | CA1CA2CA12CA7CA9 | |
| Hydrochloric Acid SCHEMBL28263909 | 0.69 | TUBB4A (0.57) | NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6660751-B1 | Sulfonamide derivatives as 5-HT7 receptor antagonists | SMITHKLINE BEECHAM P.L.C. (GB) | 2003-12-09 | — | — | US | disclosed |
| EP-0165588-B1 | ANALYTICAL REAGENT, ANALYTICAL METHOD, AND MULTILAYER CHEMICAL-ANALYTICAL ELEMENT | FUJI PHOTO FILM CO., LTD. (JP) | 1990-05-02 | — | — | EP | disclosed |
| US-4721670-A | Analytical reagent, analytical method, and multilayer chemical-analytical element | FUJI PHOTO FILM CO., LTD. (JP) | 1988-01-26 | — | — | US | disclosed |
| EP-0165588-A2 | Analytical reagent, analytical method, and multilayer chemical-analytical element | FUJI PHOTO FILM CO., LTD. (JP) | 1985-12-27 | — | — | EP | disclosed |