Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7215585 | 0.89 | FFAR2 (0.39) | CYP3A4CYP1A2PMP22LMNAMAPT | |
| SCHEMBL7216269 | 0.87 | MEN1 (0.38) | CYP3A4SMN1; SMN2CYP1A2PMP22ABCB11 | |
| SCHEMBL7220927 | 0.84 | FFAR2 (0.40) | CYP3A4CYP1A2TSHRLMNAMEN1 | |
| SCHEMBL7214263 | 0.82 | L3MBTL1 (0.54) | CYP3A4SMN1; SMN2CYP1A2PMP22LMNA | |
| SCHEMBL7221377 | 0.81 | CXCL8 (0.44) | CYP3A4CYP1A2TSHRHTTMEN1 | |
| SCHEMBL7638122 | 0.78 | FFAR2 (0.42) | CYP3A4CYP1A2MEN1KMT2AFFAR2 | |
| SCHEMBL7638474 | 0.78 | FFAR2 (0.44) | CYP3A4CYP1A2PPARAMEN1KMT2A | |
| SCHEMBL7220058 | 0.78 | FFAR2 (0.44) | SMN1; SMN2TSHRFFAR2 | |
| SCHEMBL623127 | 0.76 | SMN1; SMN2 (0.48) | CYP3A4SMN1; SMN2CYP1A2PMP22ABCB11 | |
| SCHEMBL7759971 | 0.74 | MMP8 (0.37) | SMN1; SMN2LMNAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6504046-B1 | Cyclization of nitriles using acids, to form oxazolinone chemical intermediates such as 2-phenyl-4-isopropyl-4-methyl-1,3-oxazol-5-one, used as fungicides | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2003-01-07 | — | — | US | disclosed |
| CN-1304399-A | Process for preparation of amides | IHARA CHEMICAL IND CO (JP) | 2001-07-18 | — | — | CN | disclosed |
| EP-1092705-A1 | PROCESS FOR THE PREPARATION OF AMIDES | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2001-04-18 | — | — | EP | disclosed |