Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 3/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.37 |
| ▸ | GRN | P28799 | 1/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.36 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7215585 | 0.87 | FFAR2 (0.39) | FFAR2ACKR3TRPV1LMNACYP2C9 | |
| SCHEMBL7638474 | 0.86 | FFAR2 (0.44) | FFAR2S1PR2S1PR4S1PR3ACKR3 | |
| SCHEMBL7216269 | 0.85 | MEN1 (0.38) | FFAR2ACKR3TRPV1LMNACYP2C9 | |
| SCHEMBL7220546 | 0.84 | CYP3A4 (0.39) | FFAR2LMNACYP2C9CYP3A4NFKB1 | |
| SCHEMBL7220058 | 0.83 | FFAR2 (0.44) | FFAR2ACKR3TRPV1GRNSORT1 | |
| SCHEMBL7638122 | 0.81 | FFAR2 (0.42) | FFAR2ACKR3CYP26A1HDAC4HDAC7 | |
| SCHEMBL7220957 | 0.78 | L3MBTL1 (0.56) | LMNAMEN1KMT2A | |
| SCHEMBL7219260 | 0.75 | ANO1 (0.42) | FFAR2ACKR3HDAC4HDAC7HDAC5 | |
| SCHEMBL8104975 | 0.74 | FFAR2 (0.44) | FFAR2ACKR3TRPV1HDAC4HDAC7 | |
| SCHEMBL8100402 | 0.70 | FFAR2 (0.43) | FFAR2TRPV1HDAC4HDAC7HDAC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6504046-B1 | Cyclization of nitriles using acids, to form oxazolinone chemical intermediates such as 2-phenyl-4-isopropyl-4-methyl-1,3-oxazol-5-one, used as fungicides | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2003-01-07 | — | — | US | disclosed |
| CN-1304399-A | Process for preparation of amides | IHARA CHEMICAL IND CO (JP) | 2001-07-18 | — | — | CN | disclosed |
| EP-1092705-A1 | PROCESS FOR THE PREPARATION OF AMIDES | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2001-04-18 | — | — | EP | disclosed |