Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CTSA | P10619 | 2/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 10/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7215523 | 0.87 | SOS1 (0.37) | KMT2AMEN1CRHR1MAPTMITF | |
| SCHEMBL7221634 | 0.86 | ATP1A1 (0.37) | KMT2AMEN1CTSAMAPK1AR | |
| SCHEMBL7222469 | 0.78 | CDK2 (0.34) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL7216330 | 0.78 | CD38 (0.40) | KMT2AMEN1MAPTLMNATDP1 | |
| SCHEMBL7216137 | 0.77 | PDE9A (0.37) | KMT2AMAPTNPSR1KDM4EAR | |
| SCHEMBL7222409 | 0.73 | APP (0.39) | KMT2ARAB9AMAPTLMNASMN1; SMN2 | |
| SCHEMBL7215726 | 0.71 | OPRD1 (0.37) | KMT2AMEN1CRHR1RAB9ALMNA | |
| SCHEMBL7217987 | 0.68 | CCNE2 (0.40) | KMT2AMEN1GAA | |
| SCHEMBL27592593 | 0.67 | PTPN1 (0.46) | KMT2AMEN1RAB9AMAPTLMNA | |
| SCHEMBL7215736 | 0.65 | ATP1A1 (0.36) | CTSARAB9AIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596739-B2 | Anticarcinogenic agents, cardiovascular disorders and antiinflammatory agents | THE PROCTER & GAMBLE COMPANY | 2003-07-22 | — | — | US | claimed |