Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 7/20 | 0.39 |
| ▸ | NQO2 | P16083 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
| ▸ | PROC | P04070 | 1/20 | 0.34 |
| ▸ | HPN | P05981 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.34 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7119786 | 0.94 | F2 (0.47) | F2NQO2SLC22A2F10PLG | |
| SCHEMBL7223673 | 0.88 | F2 (0.39) | F2HDAC1KDM4ENPC1RAB9A | |
| SCHEMBL7219009 | 0.86 | F2 (0.41) | F2HDAC1KDM4ENPC1RAB9A | |
| SCHEMBL7217499 | 0.85 | F2 (0.42) | F2HDAC1KDM4ENPC1RAB9A | |
| SCHEMBL7219016 | 0.83 | CA12 (0.41) | F2HDAC1KDM4ENPC1RAB9A | |
| SCHEMBL7216888 | 0.83 | F2 (0.37) | F2HDAC1KDM4ENPC1RAB9A | |
| SCHEMBL7218890 | 0.83 | NTRK1 (0.40) | F2KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL7216788 | 0.83 | KDM4E (0.39) | F2HDAC1KDM4ENPC1RAB9A | |
| SCHEMBL7224671 | 0.83 | NTRK1 (0.40) | F2HDAC1KDM4ENPC1RAB9A | |
| SCHEMBL7120809 | 0.82 | F2 (0.47) | F2NQO2SLC22A2F10PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6656956-B2 | Tryptase inhibitor; antiinflamamtory agents, antiallergens | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-12-02 | — | — | US | disclosed |