Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.38 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7218777 | 0.93 | F2 (0.51) | F2HDAC6ACHE | |
| SCHEMBL7217499 | 0.90 | F2 (0.42) | F2HDAC1HDAC8KDM4ENPC1 | |
| SCHEMBL7216788 | 0.87 | KDM4E (0.39) | F2HDAC1KDM4ENPC1RAB9A | |
| SCHEMBL7223673 | 0.86 | F2 (0.39) | F2HDAC1HDAC8KDM4ENPC1 | |
| SCHEMBL7222891 | 0.86 | F2 (0.39) | F2HDAC1OPRM1HDAC8KDM4E | |
| SCHEMBL7219016 | 0.86 | CA12 (0.41) | F2HDAC1KDM4ENPC1RAB9A | |
| SCHEMBL7224671 | 0.85 | NTRK1 (0.40) | F2HDAC6HDAC1KDM4ENPC1 | |
| SCHEMBL7218890 | 0.85 | NTRK1 (0.40) | F2KDM4ENPC1RAB9AKMT2A | |
| SCHEMBL7216989 | 0.85 | F2 (0.47) | F2 | |
| SCHEMBL7222786 | 0.85 | NTRK1 (0.44) | F2HDAC1KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6656956-B2 | Tryptase inhibitor; antiinflamamtory agents, antiallergens | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-12-02 | — | — | US | disclosed |