Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7231932 | 0.92 | HTR4 (0.38) | SLC6A2SLC6A4SLC6A3HTR4 | |
| SCHEMBL7225338 | 0.91 | SCN9A (0.33) | SLC6A2SLC6A4SLC6A3POLBHTR4 | |
| SCHEMBL7223246 | 0.90 | SLC6A3 (0.40) | SLC6A3SCN9A | |
| SCHEMBL7234386 | 0.90 | SLC6A4 (0.40) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7225932 | 0.90 | SCN9A (0.32) | SCN9A | |
| SCHEMBL7231524 | 0.90 | HTR3E (0.36) | MMP13 | |
| SCHEMBL7230910 | 0.88 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7231298 | 0.88 | KMT2A (0.38) | POLBL3MBTL1 | |
| SCHEMBL7116208 | 0.86 | POLB (0.36) | POLBMMP13SCN9A | |
| SCHEMBL7120608 | 0.85 | POLB (0.37) | SLC6A2SLC6A4SLC6A3POLBMMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | claimed |
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | disclosed |