Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 3/20 | 0.52 |
| ▸ | RECQL | P46063 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL99697 | 0.96 | CASP1 (0.63) | CASP1TSHRSMN1; SMN2ALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL11630591 | 0.94 | CASP1 (0.61) | CASP1TSHRSMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL7218589 | 0.85 | CASP1 (0.47) | CASP1TSHRSMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL2335079 | 0.83 | KMT2A (0.55) | CASP1TSHRSMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL10434174 | 0.81 | MAPT (0.59) | CASP1TSHRSMN1; SMN2ALDH1A1CYP3A4 | |
| Thiosalicylic Acid SCHEMBL4554104 | 0.81 | MAPT (0.59) | CASP1TSHRSMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL7090488 | 0.81 | JAK2 (0.53) | CASP1TSHRSMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL28610796 | 0.81 | TSHR (0.57) | CASP1TSHRSMN1; SMN2ALDH1A1CYP3A4 | |
| Aminosalicylic Acid SCHEMBL5070587 | 0.80 | ALDH1A1 (0.67) | CASP1TSHRSMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL11630588 | 0.79 | JAK2 (0.51) | CASP1TSHRSMN1; SMN2ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120165315-A1 | MEPTAZINOL CARBAMATE PRODRUG SALTS | JOSTENS, INC. | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165315-A1 | MEPTAZINOL CARBAMATE PRODRUG SALTS | MEP1A, MEP1B, CTSZ | CASP1 688/4885TSHR 2125/4885SMN1; SMN2 3945/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.