Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 4/20 | 0.33 |
| ▸ | USP47 | Q96K76 | 4/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | CCNC | P24863 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7226168 | 0.87 | HSD17B1 (0.37) | USP7F10SLC6A3SLC6A4 | |
| SCHEMBL7234021 | 0.87 | SLC6A3 (0.39) | USP7SLC6A3SLC6A4AKT1 | |
| Hydrochloric Acid SCHEMBL7231366 | 0.86 | SLC6A3 (0.38) | USP7SLC6A3SLC6A4AKT1 | |
| SCHEMBL7233118 | 0.85 | CHRNB2 (0.39) | SLC6A3SLC6A4CHRNB4CHRNA3 | |
| SCHEMBL7232268 | 0.85 | HDAC3 (0.34) | F10 | |
| SCHEMBL7231859 | 0.85 | HDAC3 (0.34) | F10SLC6A3SLC6A4AKT1 | |
| SCHEMBL7232598 | 0.84 | SLC6A3 (0.39) | SLC6A3SLC6A4CHRNB4CHRNA3 | |
| SCHEMBL7231950 | 0.84 | TAS1R3 (0.36) | F10SLC6A3SLC6A4CHRNB4CHRNA3 | |
| SCHEMBL7224957 | 0.84 | TAS1R3 (0.36) | F10SLC6A3SLC6A4CHRNB4CHRNA3 | |
| SCHEMBL7233041 | 0.83 | SLC6A4 (0.34) | SLC6A3SLC6A4AKT1CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | claimed |
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | disclosed |