Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7225106 | 0.87 | DGAT1 (0.44) | SLC6A3DGAT1USP30 | |
| SCHEMBL7230609 | 0.86 | DGAT1 (0.38) | SLC6A3DGAT1USP30 | |
| SCHEMBL7233938 | 0.84 | USP30 (0.37) | DGAT1USP30LIPG | |
| SCHEMBL7233669 | 0.84 | CHRNA7 (0.44) | DGAT1USP30 | |
| SCHEMBL7224924 | 0.84 | DGAT1 (0.41) | SLC6A3DGAT1 | |
| SCHEMBL7232544 | 0.83 | DGAT1 (0.44) | DGAT1USP30 | |
| SCHEMBL7233275 | 0.83 | DGAT1 (0.40) | DGAT1USP30LIPG | |
| SCHEMBL7226932 | 0.82 | SLC6A3 (0.37) | SLC6A3USP30BACE1BACE2 | |
| SCHEMBL7225968 | 0.82 | USP30 (0.43) | DGAT1USP30 | |
| SCHEMBL7225526 | 0.81 | DGAT1 (0.39) | DGAT1USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | claimed |
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | disclosed |