Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 4/20 | 0.38 |
| ▸ | GSR | P00390 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.33 |
| ▸ | EPOR | P19235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8821909 | 0.88 | CPB2 (0.38) | CPB2GSRFOLH1RNPEPEPOR | |
| SCHEMBL7218411 | 0.86 | CPB2 (0.36) | CPB2GSRFOLH1RNPEPEPOR | |
| SCHEMBL7219609 | 0.84 | CPB2 (0.35) | CPB2GSRFOLH1RNPEPEPOR | |
| SCHEMBL7219138 | 0.80 | EPOR (0.38) | EPOR | |
| SCHEMBL8714819 | 0.77 | CPB2 (0.43) | CPB2GSRFOLH1RNPEP | |
| SCHEMBL7224443 | 0.76 | CPB2 (0.41) | CPB2GSRFOLH1RNPEP | |
| SCHEMBL8712693 | 0.72 | CPB2 (0.37) | CPB2GSRFOLH1RNPEPEPOR | |
| SCHEMBL7915353 | 0.70 | NOS2 (0.41) | GSR | |
| SCHEMBL8716233 | 0.69 | RNPEP (0.40) | CPB2GSRFOLH1RNPEP | |
| SCHEMBL787391 | 0.69 | GSR (0.46) | CPB2GSRFOLH1RNPEPEPOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6576780-B1 | Hydroxyamidino derivatives useful as nitric oxide synthase inhibitors | GD SEARLE & COMPANY | 2003-06-10 | — | — | US | disclosed |
| EP-0885188-B1 | HYDROXYAMIDINO DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | SEARLE & CO (US) | 2000-09-27 | — | — | EP | disclosed |
| WO-1997032844-A9 | HYDROXYAMIDINO DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | — | 1997-12-24 | — | — | WO | disclosed |