Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.53 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.53 |
| ▸ | EDNRA | P25101 | 1/20 | 0.53 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7229082 | 0.90 | KDM4E (0.50) | DRD3LMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL9775890 | 0.89 | DRD3 (0.67) | DRD3LMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL9775875 | 0.89 | DRD3 (0.56) | DRD3LMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL6603300 | 0.88 | LMNA (0.55) | DRD3LMNAKDM4EMEN1KMT2A | |
| SCHEMBL9529605 | 0.86 | LMNA (0.71) | DRD3LMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL9775868 | 0.86 | DRD3 (0.55) | DRD3LMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL7240040 | 0.86 | LMNA (0.51) | DRD3LMNAKDM4EMEN1KMT2A | |
| SCHEMBL6605971 | 0.85 | KMT2A (0.56) | DRD3LMNAKDM4EMEN1KMT2A | |
| Water SCHEMBL9775888 | 0.85 | LMNA (0.70) | DRD3LMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL9786224 | 0.83 | LMNA (0.53) | DRD3LMNACYP2C9ATP6V1B2TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6548506-B2 | 1-substituted,3-carboxy,7-fluoro,8-disubstituted amino-1,4-dihydrobenzo(b)(1,8)naphthyridin-4-ones; Useful as antimicrobial agents; topical antibiotic for wounds | AVENTIS PHARMA S.A. (FR) | 2003-04-15 | — | — | US | disclosed |
| US-20020037891-A1 | Novel benzo[1,8]naphthyridine derivatives, their preparation and pharmaceutical compositions which comprise them | AVENTIS PHARMA S.A. (FR) | 2002-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020037891-A1 | Novel benzo[1,8]naphthyridine derivatives, their preparation and pharmaceutical compositions which comprise them | ABCB11, NDUFA9, NDUFC1 | DRD3 2525/4885LMNA 1363/4885CYP2C9 111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.