Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.38 |
| ▸ | VDR | P11473 | 3/20 | 0.37 |
| ▸ | PPARD | Q03181 | 2/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.36 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7395988 | 0.83 | KDM4E (0.46) | PTPN1FFAR1KDM4ETP53HSD17B10 | |
| SCHEMBL1587088 | 0.76 | FFAR1 (0.59) | FFAR1FFAR4 | |
| SCHEMBL7228564 | 0.71 | SLC7A5 (0.41) | PTPN1SIRT2KDM4EHSD17B10 | |
| 4-Hydroxyhydrocinnamic Acid Methyl Ester SCHEMBL8767620 | 0.70 | FFAR1 (0.54) | FFAR1FFAR4 | |
| SCHEMBL7824247 | 0.70 | FFAR1 (0.54) | FFAR1HSD17B10 | |
| SCHEMBL18046156 | 0.70 | ALDH1A1 (0.53) | PTPN1SIRT2KDM4ETP53HSD17B10 | |
| Methyl 3-Phenylpropanoate SCHEMBL213543 | 0.70 | KEAP1 (0.70) | FFAR1FFAR4KDM4E | |
| SCHEMBL7283109 | 0.70 | ALDH1A1 (0.57) | HSD17B10 | |
| SCHEMBL5286882 | 0.69 | FFAR1 (0.70) | FFAR1FFAR4 | |
| SCHEMBL22922181 | 0.69 | CYP4F2 (0.59) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1133491-A1 | NOVEL BENZOFURANE DERIVATIVES, PREPARATION METHOD, USE AS MEDICINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Aventis Pharma S.A. (FR) | 2001-09-19 | — | — | EP | disclosed |
| WO-2000031070-A1 | NOVEL BENZOFURANE DERIVATIVES, PREPARATION METHOD, USE AS MEDICINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA S.A. (FR) | 2000-06-02 | — | — | WO | disclosed |