Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2652406 | 0.80 | GCGR (0.61) | MAOBMAOAMAPTALDH1A1DRD2 | |
| SCHEMBL2651308 | 0.77 | MITF (0.43) | ACHEALDH1A1SMN1; SMN2DRD2TDP1 | |
| SCHEMBL7230855 | 0.76 | MAOB (0.63) | MAOBMAOAACHEALDH1A1GAA | |
| SCHEMBL7237597 | 0.75 | DRD2 (0.41) | GAADRD2LMNAKMT2A | |
| SCHEMBL15475020 | 0.72 | ALDH1A1 (0.54) | MAOBSIGMAR1ALDH1A1DRD2KDM4E | |
| SCHEMBL3463931 | 0.70 | ALDH1A1 (0.54) | ACHEBCHEALDH1A1POLBKDM4E | |
| SCHEMBL4237405 | 0.70 | LTA4H (0.72) | ACHEBCHEKMT2A | |
| SCHEMBL15474582 | 0.70 | ALDH1A1 (0.54) | ACHEBCHEALDH1A1GAASMN1; SMN2 | |
| SCHEMBL8489470 | 0.69 | KDM4E (0.60) | SIGMAR1MAPTALDH1A1GAASMN1; SMN2 | |
| SCHEMBL2316541 | 0.69 | GRIN2D (0.64) | MAPTALDH1A1GAATDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613942-B1 | Nonpeptide; 4-hydroxy benzoic acid hydrazides | NOVO NORDISK A/S (DK) | 2003-09-02 | — | — | US | disclosed |