SCHEMBL7230929

SCHEMBL7230929

O=C(CBr)C(CF)(CF)CF

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
TRPA1 O75762 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10734018 0.72
SCHEMBL455522 0.72 TRPA1 (0.36) TSHRTRPA1
SCHEMBL7920635 0.69 TSHR (0.39) TSHRTRPA1
SCHEMBL71390 0.69
SCHEMBL12616208 0.67
SCHEMBL11272579 0.67 TRPA1 (0.36) TRPA1
Water SCHEMBL20545911 0.67
SCHEMBL5860713 0.67
SCHEMBL10899343 0.65 CASP1 (0.30)
SCHEMBL2169853 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024099398-A1 CLASS OF SULFONAMIDE COMPOUNDS CONTAINING ORTHO-FUSED HETEROCYCLE AND USE THEREOF 南京明德新药研发有限公司 2024-05-16 WO disclosed
CN-109206481-A Peptide compound, application thereof and composition containing peptide compound 凯惠科技发展(上海)有限公司 2019-01-15 CN disclosed
US-6515124-B2 (Z)-2-((2-bromo-4-(((3-hydroxybenzyl)amino)carbonyl)benzoyl) -amino)pent-2-enoic acid, for example; useful for treating psoriasis HOFFMAN-LA ROCHE INC. 2003-02-04 US disclosed
US-20020161237-A1 Dehydroamino acids HOFFMANN-LA ROCHE INC. 2002-10-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020161237-A1 Dehydroamino acids HSD3B1, CYP8B1, TH TSHR 1248/4885TRPA1 4068/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.