Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10734018 | 0.79 | — | — | |
| SCHEMBL219831 | 0.78 | CYP2D6 (0.32) | TSHR | |
| SCHEMBL11101091 | 0.76 | TRPA1 (0.38) | TRPA1TSHR | |
| SCHEMBL10981981 | 0.74 | TRPA1 (0.36) | TRPA1TSHR | |
| SCHEMBL7230929 | 0.72 | TSHR (0.35) | TRPA1TSHR | |
| SCHEMBL180091 | 0.71 | TRPA1 (0.44) | TRPA1TSHR | |
| SCHEMBL112282 | 0.71 | — | — | |
| SCHEMBL5525834 | 0.69 | — | — | |
| SCHEMBL10804129 | 0.69 | — | — | |
| SCHEMBL9619294 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3215505-B1 | PIPERIDINYLPYRAZOLOPYRIMIDINONES AND THEIR USE | Bayer Pharma AG (DE) | 2019-07-24 | — | — | EP | disclosed |
| US-10118930-B2 | Piperidinylpyrazolopyrimidinones and their use | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-11-06 | — | — | US | disclosed |
| US-20170334917-A1 | PIPERIDINYLPYRAZOLOPYRIMIDINONES AND THEIR USE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-11-23 | — | — | US | disclosed |
| EP-3215505-A1 | PIPERIDINYLPYRAZOLOPYRIMIDINONES AND THEIR USE | Bayer Pharma Aktiengesellschaft (DE) | 2017-09-13 | — | — | EP | disclosed |
| WO-2016071216-A1 | PIPERIDINYLPYRAZOLOPYRIMIDINONES AND THEIR USE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-05-12 | — | — | WO | disclosed |
| US-8445691-B2 | Heterocyclic thiosubstituted alkanol derivatives | BAYER CROPSCIENCE AG (DE) | 2013-05-21 | — | — | US | disclosed |
| US-8440836-B2 | Heterocyclic alkanol derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-05-14 | — | — | US | disclosed |
| EP-2576528-A1 | HETEROCYCLIC ALKANOL DERIVATIVES AS FUNGICIDES | Bayer CropScience AG (DE) | 2013-04-10 | — | — | EP | disclosed |
| EP-2576526-A1 | HETEROCYCLIC THIOSUBSTITUTED ALKANOL DERIVATIVES AS FUNGICIDES | Bayer Intellectual Property GmbH (DE) | 2013-04-10 | — | — | EP | disclosed |
| US-20120065062-A1 | Novel Heterocyclic Alkanol Derivatives | BAYER CROPSCIENCE AG (DE) | 2012-03-15 | — | — | US | disclosed |
| EP-0019131-B1 | FLUORINATED DERIVATIVES OF 1-TRIAZOLYL BUTANE, PROCESS FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES | BAYER AG (DE) | 1982-12-22 | — | — | EP | disclosed |
| EP-0028689-B1 | ANTIMYCOTIC AGENTS CONTAINING ACYLATED TRIAZOLYL-GAMMA-FLUOROPINACOLYL DERIVATIVES, AND THEIR PREPARATION | BAYER AG (DE) | 1982-12-01 | — | — | EP | disclosed |
| US-4359470-A | Acylated triazolyl-γ-fluoropinacolyl derivatives and their use as fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1982-11-16 | — | — | US | disclosed |
| EP-0019134-B1 | FLUORINATED 1-IMIDAZOLYL-BUTANE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION AS FUNGICIDES | BAYER AG (DE) | 1982-07-28 | — | — | EP | disclosed |
| EP-0019130-B1 | ANTIMYCOTIC AGENTS AND PROCESS FOR PREPARING THEM | BAYER AG (DE) | 1982-07-07 | — | — | EP | disclosed |
| EP-0028689-A1 | Antimycotic agents containing acylated triazolyl-gamma-fluoropinacolyl derivatives, and their preparation | BAYER AG (DE) | 1981-05-20 | — | — | EP | disclosed |
| EP-0026856-A1 | Antimycotic agent containing an acylated imidazolyl-gamma-fluorpinacolyl derivative and its preparation | BAYER AG (DE) | 1981-04-15 | — | — | EP | disclosed |
| EP-0025948-A1 | Acylated imidazolyl-gamma-fluoropinacolyl derivatives, process for their preparation and their use as fungicides | BAYER AG (DE) | 1981-04-01 | — | — | EP | disclosed |
| EP-0025949-A1 | Acylated triazolyl-gamma-fluoropinacolyl derivatives, process for their preparation and their use as fungicides | BAYER AG (DE) | 1981-04-01 | — | — | EP | disclosed |
| EP-0019134-A1 | Fluorinated 1-imidazolyl-butane derivatives, process for their preparation and their application as fungicides | BAYER AG (DE) | 1980-11-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065062-A1 | Novel Heterocyclic Alkanol Derivatives | ERG28, CBR3, MYB | TRPA1 1320/4885TSHR 3765/4885 |
| US-10118930-B2 | Piperidinylpyrazolopyrimidinones and their use | HAMP, SERPINC1, PRSS8 | TRPA1 664/4885TSHR 3606/4885 |
| US-20170334917-A1 | PIPERIDINYLPYRAZOLOPYRIMIDINONES AND THEIR USE | HAMP, SERPINC1, PRSS8 | TRPA1 664/4885TSHR 3606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.