SCHEMBL723104

SCHEMBL723104

CC(N)C(O)c1ccc(O)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.64
LMNA P02545 5/20 0.64
HIF1A Q16665 5/20 0.64
ADRA2A P08913 1/20 0.64
ADRA2C P18825 1/20 0.64
ALDH1A1 P00352 1/20 0.61
RECQL P46063 4/20 0.61
TDP1 Q9NUW8 4/20 0.61
MAPT P10636 3/20 0.61
TSHR P16473 2/20 0.61
NFKB1 P19838 2/20 0.61
ALOX15 P16050 1/20 0.61
THPO P40225 1/20 0.61
HSD17B10 Q99714 1/20 0.61
POLB P06746 1/20 0.61
APEX1 P27695 1/20 0.61
MTOR P42345 1/20 0.61
BLM P54132 1/20 0.61
KMT2A Q03164 1/20 0.61
ADRB1 P08588 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4258203 1.00 KDM4E (0.64) KDM4ELMNAHIF1AADRA2AADRA2C
SCHEMBL14465577 1.00 KDM4E (0.64) KDM4ELMNAHIF1AADRA2AADRA2C
SCHEMBL2252628 1.00 KDM4E (0.64) KDM4ELMNAHIF1AADRA2AADRA2C
SCHEMBL5174891 1.00 KDM4E (0.64) KDM4ELMNAHIF1AADRA2AADRA2C
SCHEMBL5076516 1.00 KDM4E (0.64) KDM4ELMNAHIF1AADRA2AADRA2C
SCHEMBL1262889 1.00 KDM4E (0.64) KDM4ELMNAHIF1AADRA2AADRA2C
Hydrochloric Acid SCHEMBL5082770 0.98 ALDH1A1 (0.65) KDM4ELMNAHIF1AADRA2AADRA2C
Hydrochloric Acid SCHEMBL1168030 0.98 ALDH1A1 (0.65) KDM4ELMNAHIF1AADRA2AADRA2C
Hydrochloric Acid SCHEMBL5082784 0.98 ALDH1A1 (0.65) KDM4ELMNAHIF1AADRA2AADRA2C
Hydrochloric Acid SCHEMBL7327569 0.98 ALDH1A1 (0.65) KDM4ELMNAHIF1AADRA2AADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 294 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090247781-A1 SYNTHESIS OF PHENOXYACETIC ACID DERIVATIVES KISSEI PHARMACEUTICAL CO., LTD. (JP) 2009-10-01 US claimed
CN-101252952-A Preventive or therapeutic agent for diseases caused by tear reduction KISSEI PHARMACEUTICAL (JP) 2008-08-27 CN claimed
WO-2007077140-A1 HYDROXY-NOREPHEDRINE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION BASF AKTIENGESELLSCHAFT (DE) 2007-07-12 WO claimed
US-20070088174-A1 Synthesis of phenoxyacetic acid derivatives BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2007-04-19 US claimed
CN-1751019-A Amino alcohol derivatives, pharmaceutical compositions containing the same, and use thereof KISSEI PHARMACEUTICAL (JP) 2006-03-22 CN claimed
EP-1017358-B1 REDUCTION OF HAIR GROWTH GILLETTE CO (US) 2004-08-11 EP claimed
EP-1017358-A1 REDUCTION OF HAIR GROWTH THE GILLETTE COMPANY (US) 2000-07-12 EP claimed
US-5939458-A APPLYING AN INHIBITOR OF AMINOACYL-TRNA SYNTHETASE TO THE SKIN GILLETTE COMPANY, THE 1999-08-17 US claimed
WO-1999015136-A1 REDUCTION OF HAIR GROWTH THE GILLETTE COMPANY (US) 1999-04-01 WO claimed
US-5120475-A Method for preparing microcapsules having improved pre-walls, and microcapsules and photosensitive materials produced thereby THE MEAD CORPORATION (US) 1992-06-09 US claimed
EP-0122151-B1 PRODUCTION OF PRIMARY OR SECONDARY ALCOHOL DERIVATIVES OF PHOSPHOLIPIDS BY THE ENZYMATIC TECHNIQUE MEITO SANGYO KABUSHIKI KAISHA (JP) 1989-02-15 EP claimed
US-4783402-A Production of primary or secondary alcohol derivatives of phospholipids by the enzymatic technique MEITO SANGYO KABUSHIKI KAISHA (JP) 1988-11-08 US claimed
EP-0122151-A2 Production of primary or secondary alcohol derivatives of phospholipids by the enzymatic technique MEITO SANGYO KABUSHIKI KAISHA (JP) 1984-10-17 EP claimed
US-11571390-B2 Abuse deterrent compositions and methods of use Othemo Life Sciences, Inc. (US) 2023-02-07 US disclosed
EP-3160937-B1 A NOVEL METHOD FOR SYNTHESIS OF OPTICALLY PURE BETA-AMINO ALCOHOLS EMBIO LTD (IN) 2020-12-30 EP disclosed
CN-107106533-B Synergistic composition for treating microbial infections 罗切斯特大学 2020-11-06 CN disclosed
US-4058443-A PHOTOPOLYMERIZATION, BINDER, CHLORINATED POLYOLEFIN FUJI PHOTO FILM CO., LTD. (JA) 1977-11-15 US disclosed
US-4050936-A Image forming process with photopolymer layers between a support and a substrate FUJI PHOTO FILM CO., LTD. (JA) 1977-09-27 US disclosed
US-4048253-A HEAT TREATMENT FUJI PHOTO FILM CO., LTD. (JA) 1977-09-13 US disclosed
US-4010191-A Acyl derivatives of substituted bis-arylalkylamino compounds DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) 1977-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070088174-A1 Synthesis of phenoxyacetic acid derivatives DDC, PAH, HPD KDM4E 422/4885LMNA 2880/4885HIF1A 861/4885
US-20090247781-A1 SYNTHESIS OF PHENOXYACETIC ACID DERIVATIVES DDC, PAH, HPD KDM4E 414/4885LMNA 3124/4885HIF1A 818/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.