SCHEMBL1262889

SCHEMBL1262889

CC(N)[C@@H](O)c1ccc(O)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.64
LMNA P02545 5/20 0.64
HIF1A Q16665 5/20 0.64
ADRA2A P08913 1/20 0.64
ADRA2C P18825 1/20 0.64
ALDH1A1 P00352 1/20 0.61
RECQL P46063 4/20 0.61
TDP1 Q9NUW8 4/20 0.61
MAPT P10636 3/20 0.61
TSHR P16473 2/20 0.61
NFKB1 P19838 2/20 0.61
ALOX15 P16050 1/20 0.61
THPO P40225 1/20 0.61
HSD17B10 Q99714 1/20 0.61
POLB P06746 1/20 0.61
APEX1 P27695 1/20 0.61
MTOR P42345 1/20 0.61
BLM P54132 1/20 0.61
KMT2A Q03164 1/20 0.61
ADRB1 P08588 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4258203 1.00 KDM4E (0.64) KDM4ELMNAHIF1AADRA2AADRA2C
SCHEMBL14465577 1.00 KDM4E (0.64) KDM4ELMNAHIF1AADRA2AADRA2C
SCHEMBL2252628 1.00 KDM4E (0.64) KDM4ELMNAHIF1AADRA2AADRA2C
SCHEMBL5174891 1.00 KDM4E (0.64) KDM4ELMNAHIF1AADRA2AADRA2C
SCHEMBL5076516 1.00 KDM4E (0.64) KDM4ELMNAHIF1AADRA2AADRA2C
SCHEMBL723104 1.00 KDM4E (0.64) KDM4ELMNAHIF1AADRA2AADRA2C
Hydrochloric Acid SCHEMBL5082770 0.98 ALDH1A1 (0.65) KDM4ELMNAHIF1AADRA2AADRA2C
Hydrochloric Acid SCHEMBL1168030 0.98 ALDH1A1 (0.65) KDM4ELMNAHIF1AADRA2AADRA2C
Hydrochloric Acid SCHEMBL5082784 0.98 ALDH1A1 (0.65) KDM4ELMNAHIF1AADRA2AADRA2C
Hydrochloric Acid SCHEMBL7327569 0.98 ALDH1A1 (0.65) KDM4ELMNAHIF1AADRA2AADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110891562-B Lithium salts of N-substituted glycine compounds and uses thereof 心悦生医股份有限公司 2024-07-16 CN claimed
US-20090247781-A1 SYNTHESIS OF PHENOXYACETIC ACID DERIVATIVES KISSEI PHARMACEUTICAL CO., LTD. (JP) 2009-10-01 US claimed
US-20070088174-A1 Synthesis of phenoxyacetic acid derivatives BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2007-04-19 US claimed
US-4191777-A Maleic acid halfamides having blood pressure raising activity DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1980-03-04 US claimed
US-20250134870-A1 PATHWAY MODULATOR, PHARMACEUTICAL COMPOSITION HAVING SAME, USE THEREOF, AND THERAPEUTIC METHOD USING SAME JIANGSU YAHONG MEDITECH CO., LTD. (CN) 2025-05-01 US disclosed
CN-110891562-B Lithium salts of N-substituted glycine compounds and uses thereof 心悦生医股份有限公司 2024-07-16 CN disclosed
US-11906512-B2 Integrated device for analyte testing, confirmation, and donor identity verification Zeus Diagnostics, LLC (US) 2024-02-20 US disclosed
CN-111479806-B D-amino acid oxidase inhibitors and therapeutic uses thereof 心悦生医股份有限公司 2024-01-30 CN disclosed
EP-4285898-A1 PATHWAY MODULATOR, PHARMACEUTICAL COMPOSITION HAVING SAME, USE THEREOF, AND THERAPEUTIC METHOD USING SAME Jiangsu Yahong Meditech Co., Ltd. (CN) 2023-12-06 EP disclosed
CN-116490177-A Pathway modulator, pharmaceutical composition containing the same, use thereof, and therapeutic method using the same 江苏亚虹医药科技股份有限公司 2023-07-25 CN disclosed
EP-3490554-B1 USES OF DOPAMINE BETA-HYDROXYLASE (DBH) INHIBITORS FOR THE TREATMENT OF CANCER JIANGSU YAHONG MEDITECH CO LTD (CN) 2023-07-05 EP disclosed
US-11571390-B2 Abuse deterrent compositions and methods of use Othemo Life Sciences, Inc. (US) 2023-02-07 US disclosed
EP-0586585-A1 1,2-DIHYDROPYRIDO(3,4-B)PYRAZINES AS FUNGICIDES SOUTHERN RESEARCH INSTITUTE (US) 1994-03-16 EP disclosed
EP-0405344-B1 2-AMINO-1,2,3,4,-TETRAHYDRONAPHTHALENE DERIVATIVES WITH CARDIOVASCULAR ACTIVITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM CHIESI FARMACEUTICI S.p.A. (IT) 1993-09-01 EP disclosed
WO-1992020680-A1 1,2-DIHYDROPYRIDO(3,4-B)PYRAZINES AS FUNGICIDES SOUTHERN RESEARCH INSTITUTE (US) 1992-11-26 WO disclosed
US-5096929-A Inotropic agents; vasodilation CHIESI FARMACEUTICI S.P.A. (IT) 1992-03-17 US disclosed
US-5095017-A 1,2-dihydropyrido(3,4,-b)pyrazines as fungicides SOUTHERN RESEARCH INSTITUTE (US) 1992-03-10 US disclosed
EP-0405344-A2 2-Amino-1,2,3,4,-tetrahydronaphthalene derivatives with cardiovascular activity, process for their preparation and pharmaceutical compositions containing them CHIESI FARMACEUTICI S.p.A. (IT) 1991-01-02 EP disclosed
US-4226803-A Process for production of optically active bases DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1980-10-07 US disclosed
US-4191777-A Maleic acid halfamides having blood pressure raising activity DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1980-03-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070088174-A1 Synthesis of phenoxyacetic acid derivatives DDC, PAH, HPD KDM4E 422/4885LMNA 2880/4885HIF1A 861/4885
US-20090247781-A1 SYNTHESIS OF PHENOXYACETIC ACID DERIVATIVES DDC, PAH, HPD KDM4E 414/4885LMNA 3124/4885HIF1A 818/4885
US-20250134870-A1 PATHWAY MODULATOR, PHARMACEUTICAL COMPOSITION HAVING SAME, USE THEREOF, AND THERAPEUTIC METHOD USING SAME DBH, COMT, ADRB1 KDM4E 2506/4885LMNA 4831/4885HIF1A 1990/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.