SCHEMBL7236902

SCHEMBL7236902

COc1cc(Cl)nc(C(=O)NS(=O)(=O)c2ccccc2S(C)(=O)=O)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GCK P35557 1/20 0.40
MAPK1 P28482 1/20 0.39
ALKBH2 Q6NS38 1/20 0.38
ALKBH3 Q96Q83 1/20 0.38
KAT6A Q92794 4/20 0.38
FLT1 P17948 4/20 0.38
FLT4 P35916 4/20 0.38
KDR P35968 4/20 0.38
PTGS1 P23219 2/20 0.37
PTGS2 P35354 2/20 0.37
MEN1 O00255 1/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
KMT2A Q03164 1/20 0.37
TLR9 Q9NR96 1/20 0.37
KDM4E B2RXH2 1/20 0.37
LMNA P02545 1/20 0.37
HTT P42858 1/20 0.37
HSD11B1 P28845 1/20 0.37
JAK2 O60674 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7226876 0.89 FLT1 (0.49) ALKBH2ALKBH3FLT1FLT4KDR
SCHEMBL7227157 0.88 ALDH1A1 (0.38) MAPK1ALKBH2ALKBH3FLT1FLT4
SCHEMBL7226908 0.86 KMT2A (0.44) MAPK1FLT1FLT4KDRMEN1
SCHEMBL7235392 0.86 ALKBH2 (0.35) ALKBH2ALKBH3KAT6AFLT1FLT4
SCHEMBL7233649 0.85 CCR4 (0.47) FLT1FLT4KDR
SCHEMBL7227192 0.83 FBP1 (0.51) ALKBH2ALKBH3
SCHEMBL7235501 0.81 FLT1 (0.44) FLT1FLT4KDRPTGS1PTGS2
SCHEMBL7227318 0.80 ALDH1A1 (0.42) MAPK1KAT6AFLT1FLT4KDR
SCHEMBL7226318 0.74 CA1 (0.45) MAPK1ALKBH2ALKBH3FLT1FLT4
SCHEMBL7236917 0.74 CA1 (0.45) ALKBH2ALKBH3MEN1NPC1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6610853-B1 N-(phenylsulfonyl)picolinamide derivatives, process for producing the same, and herbicide KUREHA KAGAKU KOGYO K.K. (JP) 2003-08-26 US disclosed
EP-1069112-A1 N-(PHENYLSULFONYL) PICOLINAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND HERBICIDE KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2001-01-17 EP disclosed