SCHEMBL7238518

SCHEMBL7238518

COc1ccc(O)c(B(O)O)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 1/20 0.55
ALDH1A1 P00352 2/20 0.53
KDM4E B2RXH2 1/20 0.53
MEN1 O00255 1/20 0.53
GAA P10253 1/20 0.53
MAPT P10636 1/20 0.53
THRB P10828 1/20 0.53
RECQL P46063 1/20 0.53
BLM P54132 1/20 0.53
KMT2A Q03164 1/20 0.53
MCL1 Q07820 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
ENPP2 Q13822 2/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
TRIM24 O15164 1/20 0.50
TYR P14679 1/20 0.50
TRIM33 Q9UPN9 1/20 0.50
NPC1 O15118 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29952460 1.00 ERN1 (0.55) ERN1ALDH1A1KDM4EMEN1GAA
SCHEMBL29957088 0.84 TRIM24 (0.57) ERN1ALDH1A1KDM4EMEN1GAA
SCHEMBL8696330 0.84 TRIM24 (0.57) ERN1ALDH1A1KDM4EMEN1GAA
SCHEMBL518510 0.78 TUBB4A (0.59) ALDH1A1MEN1GAAMAPTTHRB
SCHEMBL1960037 0.78 ENPP2 (0.50) ERN1ALDH1A1KDM4EMEN1GAA
SCHEMBL29385414 0.78 TUBB4A (0.59) ALDH1A1MEN1GAAMAPTTHRB
SCHEMBL4145654 0.78 NQO1 (0.48) ALDH1A1KDM4EMEN1GAAMAPT
SCHEMBL645367 0.77 ENPP2 (0.48) ERN1ALDH1A1KDM4EMEN1GAA
SCHEMBL9935773 0.77 ENPP2 (0.48) ERN1ALDH1A1KDM4EMEN1GAA
SCHEMBL3789771 0.77 ALDH1A1 (0.53) ERN1ALDH1A1KDM4EMEN1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118515534-B Multi-tooth ligand, multi-tooth ligand metal catalyst, and preparation method and application thereof 华南理工大学 2024-11-05 CN claimed
CN-118515534-A Multi-tooth ligand, multi-tooth ligand metal catalyst, and preparation method and application thereof 华南理工大学 2024-08-20 CN claimed
US-12264159-B2 Functionalized heterocycles as antiviral agents ENANTA PHARMACEUTICALS, INC. (US) 2025-04-01 US disclosed
CN-118515534-B Multi-tooth ligand, multi-tooth ligand metal catalyst, and preparation method and application thereof 华南理工大学 2024-11-05 CN disclosed
CN-118515534-A Multi-tooth ligand, multi-tooth ligand metal catalyst, and preparation method and application thereof 华南理工大学 2024-08-20 CN disclosed
US-20240262828-A1 Functionalized Heterocycles as Antiviral Agents ENANTA PHARM INC (US) 2024-08-08 US disclosed
US-11891393-B2 Functionalized heterocycles as antiviral agents ENANTA PHARMACEUTICALS, INC. (US) 2024-02-06 US disclosed
US-20230075366-A1 FUNCTIONALIZED HETEROCYCLES AS ANTIVIRAL AGENTS ENANTA PHARM INC (US) 2023-03-09 US disclosed
US-11198693-B2 Functionalized heterocycles as antiviral agents ENANTA PHARMACEUTICALS, INC. (US) 2021-12-14 US disclosed
EP-3883570-A1 FUNCTIONALIZED HETEROCYCLES AS ANTIVIRAL AGENTS Enanta Pharmaceuticals, Inc. (US) 2021-09-29 EP disclosed
WO-2021147882-A1 DIBENZOFURAN DERIVATIVE CATHEPSIN K INHIBITOR, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF 深圳信立泰药业股份有限公司 2021-07-29 WO disclosed
US-20200165249-A1 FUNCTIONALIZED HETEROCYCLES AS ANTIVIRAL AGENTS ENANTA PHARMACEUTICALS, INC. 2020-05-28 US disclosed
US-10173985-B2 Aminoindazole derivatives as sodium channel inhibitors ALMIRALL, S.A. (ES) 2019-01-08 US disclosed
US-20180244626-A1 AMINOINDAZOLE DERIVATIVES AS SODIUM CHANNEL INHIBITORS ALMIRALL, S.A. (ES) 2018-08-30 US disclosed
EP-3274335-A1 AMINOINDAZOLE DERIVATIVES AS SODIUM CHANNEL INHIBITORS Almirall S.A. (ES) 2018-01-31 EP disclosed
WO-2016150971-A1 AMINOINDAZOLE DERIVATIVES AS SODIUM CHANNEL INHIBITORS ALMIRALL, S.A. (ES) 2016-09-29 WO disclosed
US-6541490-B1 Treating ischemia or reoxygenation injury; preparation from a bipyridine, a benzeneboronic acid and a manganese salt EUKARION, INC. 2003-04-01 US disclosed
EP-1119573-A2 BIPYRIDINE MANGANESE COMPLEXES EUKARION, INC. (US) 2001-08-01 EP disclosed
US-6177419-B1 ANTIOXIDANT CHELATE COMPOUNDS FOR PREVENTING OXYGEN FREE RADICAL-ASSOCIATED DISEASES IN MAMMALS; NEUROPROTECTANTS, SUPEROXIDE DISMUTASE (SOD), CATALASE (CAT) AND/OR PEROXIDASE (POD) MIMETICS EUKARION, INC. 2001-01-23 US disclosed
WO-2000009512-A2 BIPYRIDINE MANGANESE COMPLEXES EUKARION, INC. (US) 2000-02-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240262828-A1 Functionalized Heterocycles as Antiviral Agents HCCS, HAVCR2, HDGF ERN1 1817/4885ALDH1A1 2352/4885KDM4E 1899/4885
US-11891393-B2 Functionalized heterocycles as antiviral agents HCCS, HAVCR2, HDGF ERN1 1817/4885ALDH1A1 2352/4885KDM4E 1899/4885
US-20230075366-A1 FUNCTIONALIZED HETEROCYCLES AS ANTIVIRAL AGENTS HCCS, HAVCR2, HDGF ERN1 1817/4885ALDH1A1 2352/4885KDM4E 1899/4885
US-20180244626-A1 AMINOINDAZOLE DERIVATIVES AS SODIUM CHANNEL INHIBITORS SCN1B, SCN1A, SCN3A ERN1 3357/4885ALDH1A1 1962/4885KDM4E 2079/4885
US-10173985-B2 Aminoindazole derivatives as sodium channel inhibitors SCN1B, SCN1A, SCN3A ERN1 3330/4885ALDH1A1 1874/4885KDM4E 1956/4885
US-11198693-B2 Functionalized heterocycles as antiviral agents HCCS, HAVCR2, HDGF ERN1 1817/4885ALDH1A1 2352/4885KDM4E 1899/4885
US-12264159-B2 Functionalized heterocycles as antiviral agents HCCS, HAVCR2, HDGF ERN1 1817/4885ALDH1A1 2352/4885KDM4E 1899/4885
US-20200165249-A1 FUNCTIONALIZED HETEROCYCLES AS ANTIVIRAL AGENTS HCCS, HAVCR2, HDGF ERN1 1817/4885ALDH1A1 2352/4885KDM4E 1899/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.