Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28278769 | 0.83 | ENPP2 (0.48) | ENPP2CA1CA2CA12CA7 | |
| SCHEMBL29385414 | 0.77 | TUBB4A (0.59) | ENPP2CA1CA2CA12CA7 | |
| SCHEMBL7238518 | 0.77 | ERN1 (0.55) | ENPP2CA1CA2CA12CA7 | |
| SCHEMBL518510 | 0.77 | TUBB4A (0.59) | ENPP2CA1CA2CA12CA7 | |
| SCHEMBL1960037 | 0.77 | ENPP2 (0.50) | ENPP2CA1CA2CA12CA7 | |
| SCHEMBL29952460 | 0.77 | ERN1 (0.55) | ENPP2CA1CA2CA12CA7 | |
| SCHEMBL15728767 | 0.76 | LTA4H (0.43) | CA1CA2CA12CA7CA9 | |
| SCHEMBL3789771 | 0.75 | ALDH1A1 (0.53) | ENPP2CA1CA2CA12CA7 | |
| SCHEMBL645367 | 0.75 | ENPP2 (0.48) | ENPP2CA1CA2CA12CA7 | |
| SCHEMBL41499 | 0.75 | ENPP2 (0.48) | ENPP2CA1CA2CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114395057-B | Polyacrylamide containing chelating sites, chelating type variable-viscosity slickwater and preparation | 中国石油大学(北京) | 2022-12-23 | — | — | CN | claimed |
| CN-114395057-A | Polyacrylamide containing chelating sites, chelating type variable-viscosity slickwater and preparation | 中国石油大学(北京) | 2022-04-26 | — | — | CN | claimed |
| CN-110155988-B | Activation method of carbon nano tube and method for preparing conductive heat-shrinkable tube | 上海长园电子材料有限公司 | 2022-03-08 | — | — | CN | claimed |
| CN-111995788-B | Polymer brush with bacterial responsiveness and preparation method thereof | 中国科学院长春应用化学研究所 | 2021-09-21 | — | — | CN | claimed |
| CN-111995788-A | Polymer brush with bacterial responsiveness and preparation method thereof | 中国科学院长春应用化学研究所 | 2020-11-27 | — | — | CN | claimed |
| US-20250162982-A1 | METHODS OF MANUFACTURING TREPROSTINIL AND TREPROSTINIL DERIVATIVE PRODRUGS | INSMED INCORPORATED (US) | 2025-05-22 | — | — | US | disclosed |
| WO-2024145422-A1 | SYNTHESIS OF 2-PHENYL-2-AMINO-CYCLOHEXAN-1-ONE DERIVATIVES | GILGAMESH PHARMACEUTICALS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |
| US-20230250051-A1 | METHODS OF MANUFACTURING TREPROSTINIL AND TREPROSTINIL DERIVATIVE PRODRUGS | INSMED INCORPORATED (US) | 2023-08-10 | — | — | US | disclosed |
| CN-114395057-B | Polyacrylamide containing chelating sites, chelating type variable-viscosity slickwater and preparation | 中国石油大学(北京) | 2022-12-23 | — | — | CN | disclosed |
| CN-114395057-A | Polyacrylamide containing chelating sites, chelating type variable-viscosity slickwater and preparation | 中国石油大学(北京) | 2022-04-26 | — | — | CN | disclosed |
| CN-110155988-B | Activation method of carbon nano tube and method for preparing conductive heat-shrinkable tube | 上海长园电子材料有限公司 | 2022-03-08 | — | — | CN | disclosed |
| EP-3904326-A1 | METHODS OF MANUFACTURING TREPROSTINIL AND TREPROSTINIL DERIVATIVE PRODRUGS | Insmed Incorporated (US) | 2021-11-03 | — | — | EP | disclosed |
| US-20140142322-A1 | Boronic Acid Catalysts and Methods of Use Thereof for Activation and Transformation of Carboxylic Acids | GREENCENTRE CANADA (CA) | 2014-05-22 | — | — | US | disclosed |
| US-20140142322-A1 | Boronic Acid Catalysts and Methods of Use Thereof for Activation and Transformation of Carboxylic Acids | GREENCENTRE CANADA (CA) | 2014-05-22 | — | — | US | disclosed |
| US-20140142322-A1 | Boronic Acid Catalysts and Methods of Use Thereof for Activation and Transformation of Carboxylic Acids | GREENCENTRE CANADA (CA) | 2014-05-22 | — | — | US | disclosed |
| US-20140076810-A1 | Systems and Methods for Use of Water with Switchable Ionic Strength | Greencentre Canaga (US) | 2014-03-20 | — | — | US | disclosed |
| EP-2675816-A1 | BORONIC ACID CATALYSTS AND METHODS OF USE THEREOF FOR ACTIVATION AND TRANSFORMATION OF CARBOXYLIC ACIDS | The Governors of the University of Alberta (CA) | 2013-12-25 | — | — | EP | disclosed |
| EP-2651992-A1 | SYSTEMS AND METHODS FOR USE OF WATER WITH SWITCHABLE IONIC STRENGTH | Queen's University At Kingston (CA) | 2013-10-23 | — | — | EP | disclosed |
| WO-2012109749-A1 | BORONIC ACID CATALYSTS AND METHODS OF USE THEREOF FOR ACTIVATION AND TRANSFORMATION OF CARBOXYLIC ACIDS | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2012-08-23 | — | — | WO | disclosed |
| WO-2012079175-A1 | SYSTEMS AND METHODS FOR USE OF WATER WITH SWITCHABLE IONIC STRENGTH | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230250051-A1 | METHODS OF MANUFACTURING TREPROSTINIL AND TREPROSTINIL DERIVATIVE PRODRUGS | PTGIS, THOP1, PTGIR | ENPP2 246/4885CA1 1313/4885CA2 1826/4885 |
| US-20140142322-A1 | Boronic Acid Catalysts and Methods of Use Thereof for Activation and Transformation of Carboxylic Acids | BCAT1, ME1, BCAT2 | ENPP2 1712/4885CA1 21/4885CA2 91/4885 |
| US-20250162982-A1 | METHODS OF MANUFACTURING TREPROSTINIL AND TREPROSTINIL DERIVATIVE PRODRUGS | PTGIS, PTGER1, PTGIR | ENPP2 645/4885CA1 1353/4885CA2 1921/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.