SCHEMBL7238745

SCHEMBL7238745

CSCCN1CCCCC1

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
TSHR P16473 2/20 0.48
HRH3 Q9Y5N1 2/20 0.48
CARM1 Q86X55 1/20 0.42
PRMT6 Q96LA8 1/20 0.42
PRMT8 Q9NR22 1/20 0.42
ALOX15 P16050 1/20 0.40
POLB P06746 1/20 0.39
MAPT P10636 1/20 0.39
CYP1A2 P05177 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
LMNA P02545 2/20 0.37
MAPK1 P28482 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
GAA P10253 1/20 0.36
SIGMAR1 Q99720 1/20 0.35
LTA4H P09960 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10061913 0.97
SCHEMBL31194974 0.90 POLB (0.41) ALDH1A1TSHRHRH3CARM1PRMT6
SCHEMBL31194969 0.90 POLB (0.41) ALDH1A1TSHRHRH3CARM1PRMT6
SCHEMBL31194972 0.86 ALOX15 (0.38) ALDH1A1TSHRCARM1PRMT6PRMT8
SCHEMBL17209067 0.85 HRH3 (0.56) ALDH1A1TSHRHRH3CARM1PRMT6
SCHEMBL18520145 0.82 HRH3 (0.52) ALDH1A1TSHRHRH3CARM1PRMT6
SCHEMBL24160080 0.81 HRH3 (0.65) ALDH1A1TSHRHRH3ALOX15MAPT
SCHEMBL16943890 0.79 PAOX (0.38) ALOX15CYP1A2LMNASIGMAR1
SCHEMBL19969485 0.78 HTR1A (0.38) ALDH1A1TSHRALOX15CYP1A2
SCHEMBL4173915 0.78 HRH3 (0.52) ALDH1A1TSHRHRH3CARM1PRMT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024123633-A1 LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF RECODE THERAPEUTICS, INC. (US) 2024-06-13 WO disclosed
US-20230338411-A1 COMPOSITIONS AND METHODS FOR TARGETED DELIVERY TO CELLS RECODE THERAPEUTICS, INC. 2023-10-26 US disclosed
WO-2023131277-A1 NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF 药捷安康(南京)科技股份有限公司 2023-07-13 WO disclosed
US-20230161252-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-25 US disclosed
US-20230161252-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-25 US disclosed
US-20230161255-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-25 US disclosed
WO-2022087634-A1 CTPS1 INHIBITORS AND USES THEREOF NIMBUS CLOTHO, INC. (US) 2022-04-28 WO disclosed
US-11040954-B1 CXCR3 receptor agonists RECEPTOS LLC (US) 2021-06-22 US disclosed
EP-3643717-B1 7-SUBSTITUTED PYRROLE TRIAZINE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, AND PREPARATION METHOD THEREFOR AND USES THEREOF SHANGHAI INST MATERIA MEDICA CAS (CN) 2021-06-02 EP disclosed
US-20150203526-A1 NOVEL 19-NOR-STEROIDS AND THEIR USE FOR TREATING PROGESTERONE- DEPENDENT CONDITIONS REPROS THERAPEUTICS INC. (US) 2015-07-23 US disclosed
US-20130274234-A1 NOVEL 19-NOR-STEROIDS AND THEIR USE FOR TREATING PROGESTERONE- DEPENDENT CONDITIONS REPROS THERAPEUTICS INC. (US) 2013-10-17 US disclosed
US-20130018027-A1 COMPOSITIONS AND METHODS FOR NON-TOXIC DELIVERY OF ANTIPROGESTINS REPROS THERAPEUTICS INC. (US) 2013-01-17 US disclosed
US-7279489-B2 Compounds and methods for modulation of estrogen receptors SIGNAL PHARMACEUTICALS, LLC (US) 2007-10-09 US disclosed
US-6639109-B1 Reacting amino alcohol with sulfuric acid then reacting resulting amino sulfate with a mercaptan; simple, safe, rapid NIHON NOHYAKU CO., LTD. (JP) 2003-10-28 US disclosed
EP-1216988-A1 THIOALKYLAMINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF Nihon Nohyaku Co., Ltd. (JP) 2002-06-26 EP disclosed
US-5215967-A AMINOACID DERIVATIVES INHIBITING RENIN MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1993-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150203526-A1 NOVEL 19-NOR-STEROIDS AND THEIR USE FOR TREATING PROGESTERONE- DEPENDENT CONDITIONS HSD17B11, CYP19A1, ESRRB ALDH1A1 672/4885TSHR 288/4885HRH3 2909/4885
US-11040954-B1 CXCR3 receptor agonists CXCR3, CXCR1, CCR7 ALDH1A1 1802/4885TSHR 274/4885HRH3 141/4885
US-20130018027-A1 COMPOSITIONS AND METHODS FOR NON-TOXIC DELIVERY OF ANTIPROGESTINS PGF, CYP19A1, GNRHR ALDH1A1 1319/4885TSHR 285/4885HRH3 2358/4885
US-20230338411-A1 COMPOSITIONS AND METHODS FOR TARGETED DELIVERY TO CELLS CHMP4B, LIPA, NPC1L1 ALDH1A1 4006/4885TSHR 2262/4885HRH3 1656/4885
US-20130274234-A1 NOVEL 19-NOR-STEROIDS AND THEIR USE FOR TREATING PROGESTERONE- DEPENDENT CONDITIONS HSD17B11, CYP19A1, ESRRB ALDH1A1 672/4885TSHR 288/4885HRH3 2909/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.