Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7238745 | 0.78 | ALDH1A1 (0.48) | ALDH1A1TSHRCYP1A2ALOX15 | |
| SCHEMBL10061913 | 0.75 | — | — | |
| SCHEMBL23074891 | 0.75 | NOS3 (0.36) | — | |
| SCHEMBL31194972 | 0.75 | ALOX15 (0.38) | ALDH1A1TSHRALOX15 | |
| SCHEMBL19969935 | 0.73 | HTR1A (0.39) | HTR1AADRA1BCYP1A2CYP2D6ALOX15 | |
| SCHEMBL31194974 | 0.73 | POLB (0.41) | ALDH1A1TSHRALOX15 | |
| SCHEMBL31194969 | 0.73 | POLB (0.41) | ALDH1A1TSHRALOX15 | |
| SCHEMBL11605309 | 0.72 | KMT2A (0.41) | HTR1AADRA1BALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL11605451 | 0.72 | HTR1A (0.45) | HTR1AADRA1BALDH1A1TSHRCYP1A2 | |
| SCHEMBL11607837 | 0.72 | HTR1A (0.45) | HTR1AADRA1BALDH1A1TSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180072677-A1 | Peptidomimetics and Methods of Using the Same | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2018-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180072677-A1 | Peptidomimetics and Methods of Using the Same | OPRM1, OPRL1, OPRD1 | HTR1A 226/4885ADRA1B 113/4885ALDH1A1 1575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.