Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7250610 | 0.79 | KDM1A (0.46) | CYP3A4SLC6A3CYP2D6MCHR1SLC6A2 | |
| SCHEMBL7250161 | 0.78 | OPRD1 (0.43) | SLC6A3CYP2D6SLC6A2SLC6A4TSHR | |
| SCHEMBL31558350 | 0.78 | LTB4R (0.53) | LTB4RLTB4R2TSHR | |
| SCHEMBL7244280 | 0.76 | HTR6 (0.46) | LTB4RLTB4R2TSHR | |
| SCHEMBL7241734 | 0.76 | HTR6 (0.46) | SLC6A3CYP2D6SLC6A2LTB4RLTB4R2 | |
| SCHEMBL7249487 | 0.76 | HTR6 (0.46) | ALDH1A1LTB4RLTB4R2LMNATSHR | |
| SCHEMBL7249674 | 0.75 | BLM (0.41) | ALDH1A1LTB4RLTB4R2LMNATSHR | |
| SCHEMBL7246265 | 0.75 | LTB4R (0.43) | TAS1R3TAS1R1LTB4RLTB4R2KMT2A | |
| SCHEMBL7243321 | 0.75 | ALDH1A1 (0.42) | CYP3A4SLC6A3CYP2D6MCHR1SLC6A2 | |
| SCHEMBL7243291 | 0.73 | ALDH1A1 (0.49) | HCRTR1ALDH1A1LTB4RLTB4R2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030191279-A1 | Urea derivatives useful as anticancer agents | GOLDSTEIN STEVEN WAYNE (US) | 2003-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030191279-A1 | Urea derivatives useful as anticancer agents | CCNA1, CCNE1, CCND1 | CYP3A4 1029/4885SLC6A3 4259/4885CYP2D6 1297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.