SCHEMBL7246265

SCHEMBL7246265

OC1c2ccccc2CCC1Cc1cccc(F)c1

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LTB4R Q15722 4/20 0.43
LTB4R2 Q9NPC1 4/20 0.43
BLM P54132 1/20 0.41
TSHR P16473 1/20 0.41
TRPA1 O75762 1/20 0.40
TAS1R3 Q7RTX0 1/20 0.40
TAS1R1 Q7RTX1 1/20 0.40
TAS1R2 Q8TE23 1/20 0.40
PIN1 Q13526 1/20 0.40
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7244280 0.85 HTR6 (0.46) LTB4RLTB4R2BLMTSHRPIN1
SCHEMBL31558350 0.84 LTB4R (0.53) LTB4RLTB4R2BLMTSHR
SCHEMBL7249674 0.84 BLM (0.41) LTB4RLTB4R2BLMTSHR
SCHEMBL7244243 0.81 LTB4R (0.47) LTB4RLTB4R2KMT2A
SCHEMBL7247898 0.79 GRIN2B (0.45) TAS1R3TAS1R1TAS1R2
SCHEMBL7250161 0.78 OPRD1 (0.43) BLMTSHR
SCHEMBL7241734 0.76 HTR6 (0.46) LTB4RLTB4R2BLMTSHR
SCHEMBL7249487 0.76 HTR6 (0.46) LTB4RLTB4R2BLMTSHR
SCHEMBL7241908 0.75 CYP3A4 (0.50) LTB4RLTB4R2TSHRTAS1R3TAS1R1
SCHEMBL7242002 0.74 OPRM1 (0.39) LTB4RLTB4R2TAS1R3TAS1R1TAS1R2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030191279-A1 Urea derivatives useful as anticancer agents GOLDSTEIN STEVEN WAYNE (US) 2003-10-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030191279-A1 Urea derivatives useful as anticancer agents CCNA1, CCNE1, CCND1 LTB4R 3845/4885LTB4R2 4204/4885BLM 952/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.